C
Christopher A. Bradfield
Researcher at University of California, Berkeley
Publications - 1
Citations - 569
Christopher A. Bradfield is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Monooxygenase & Indole-3-carbinol. The author has an hindex of 1, co-authored 1 publications receiving 534 citations.
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Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Leonard F. Bjeldanes,Jin-Young Kim,Karl R. Grose,James C. Bartholomew,Christopher A. Bradfield +4 more
TL;DR: The aromatic hydrocarbon responsiveness-receptor Kd values are reported and it is shown that indolo[3,2-b]carbazole (ICZ) is produced from I3C in yields on the order of 0.01% in vitro and, after oral intubation, in vivo, and ICZ and related condensation products appear responsible for the enzyme-inducing effects of dietary I2C.