C
Christopher Chen
Researcher at National University of Singapore
Publications - 485
Citations - 21830
Christopher Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Dementia & Stroke. The author has an hindex of 63, co-authored 410 publications receiving 16308 citations. Previous affiliations of Christopher Chen include Singapore General Hospital & University Health System.
Papers
More filters
Journal ArticleDOI
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
Joanna M. Wardlaw,Eric E. Smith,Geert J. Biessels,Charlotte Cordonnier,Franz Fazekas,Richard Frayne,Richard I. Lindley,John T. O'Brien,Frederik Barkhof,Oscar R. Benavente,Sandra E. Black,Carol Brayne,Monique M.B. Breteler,Hugues Chabriat,Charles DeCarli,Frank-Erik de Leeuw,Fergus N. Doubal,Marco Duering,Nick C. Fox,Steven M. Greenberg,Vladimir Hachinski,Ingo Kilimann,Vincent Mok,Robert J. van Oostenbrugge,Leonardo Pantoni,Oliver Speck,Blossom C. M. Stephan,Stefan J. Teipel,Anand Viswanathan,David J. Werring,Christopher Chen,Colin Smith,Mark A. van Buchem,Bo Norrving,Philip B. Gorelick,Martin Dichgans +35 more
TL;DR: This Position Paper summarises the main outcomes of this international effort to provide the STandards for ReportIng Vascular changes on nEuroimaging (STRIVE).
Journal ArticleDOI
Diagnostic criteria for vascular cognitive disorders: a VASCOG statement.
Perminder S. Sachdev,Raj N. Kalaria,John T. O'Brien,Ingmar Skoog,Suvarna Alladi,Sandra E. Black,Deborah Blacker,Dan G. Blazer,Christopher Chen,Helena C. Chui,Mary Ganguli,Kurt A. Jellinger,Dilip V. Jeste,Florence Pasquier,Jane S. Paulsen,Niels D. Prins,Kenneth Rockwood,Gustavo C. Roman,Philip Scheltens +18 more
TL;DR: The proposed criteria for VCD provide a coherent approach to the diagnosis of this diverse group of disorders, with a view to stimulating clinical and pathologic validation studies and can be harmonized with the DSM-5 criteria.
Journal ArticleDOI
Cloning of the essential myotonic dystrophy region and mapping of the putative defect
C. Aslanidis,G Jansen,Chris T. Amemiya,G Shutler,Mani S. Mahadevan,Catherine Tsilfidis,Christopher Chen,J. Alleman,Wormskamp Ng,Vooijs M +9 more
TL;DR: The physical map location and the genetic characteristics of the length polymorphism is compatible with a direct role in the pathogenesis of myotonic dystrophy and shows similarities to the instability seen at the fragile X locus.
Journal ArticleDOI
Vascular dysfunction-The disregarded partner of Alzheimer's disease
Melanie D. Sweeney,Axel Montagne,Abhay P. Sagare,Daniel A. Nation,Lon S. Schneider,Helena C. Chui,Michael G. Harrington,Judy Pa,Meng Law,Danny J.J. Wang,Russell E. Jacobs,Fergus N. Doubal,Joel Ramirez,Sandra E. Black,Helene Benveniste,Martin Dichgans,Costantino Iadecola,Seth Love,Philip M.W. Bath,Philip M.W. Bath,Hugh S. Markus,Rustam Al-Shahi Salman,Stuart M. Allan,Terence J. Quinn,Rajesh N. Kalaria,David J. Werring,Roxana O. Carare,Rhian M. Touyz,Steve C.R. Williams,Michael A. Moskowitz,Zvonimir S. Katusic,Sarah E. Lutz,Orly Lazarov,Richard D. Minshall,Jalees Rehman,Thomas P. Davis,Cheryl L. Wellington,Hector M. González,Chun Yuan,Samuel N. Lockhart,Timothy M. Hughes,Christopher Chen,Perminder S. Sachdev,John T. O'Brien,Ingmar Skoog,Leonardo Pantoni,Deborah Gustafson,Geert Jan Biessels,Anders Wallin,Eric E. Smith,Vincent Mok,Adrian Wong,Peter Passmore,Frederick Barkof,Frederick Barkof,Majon Muller,Monique M.B. Breteler,Monique M.B. Breteler,Gustavo C. Román,Edith Hamel,Sudha Seshadri,Sudha Seshadri,Rebecca F. Gottesman,Mark A. van Buchem,Zoe Arvanitakis,Julie A. Schneider,Lester R. Drewes,Vladimir Hachinski,Caleb E. Finch,Arthur W. Toga,Joanna M. Wardlaw,Berislav V. Zlokovic +71 more
TL;DR: Vascular imaging biomarkers of small vessel disease of the brain, which is responsible for >50% of dementia worldwide, including AD, are already established, well characterized, and easy to recognize and should be incorporated into the AD Research Framework to gain a better understanding of AD pathophysiology and aid in treatment efforts.
Journal ArticleDOI
The Montreal Cognitive Assessment (MoCA) is superior to the Mini-Mental State Examination (MMSE) for the detection of vascular cognitive impairment after acute stroke.
Yanhong Dong,Yanhong Dong,Vivek Sharma,Bernard Poon-Lap Chan,Narayanaswamy Venketasubramanian,Hock Luen Teoh,Raymond C.S. Seet,Sophia Tanicala,Yiong Huak Chan,Christopher Chen +9 more
TL;DR: The MoCA is more sensitive than the MMSE in screening for cognitive impairment after acute stroke, and may therefore be a superior screening instrument for VCIND.