C
Christopher J. Rhodes
Researcher at University of Reading
Publications - 229
Citations - 13179
Christopher J. Rhodes is an academic researcher from University of Reading. The author has contributed to research in topics: Radical & Electron paramagnetic resonance. The author has an hindex of 23, co-authored 227 publications receiving 11073 citations. Previous affiliations of Christopher J. Rhodes include University of Sussex & University of Leicester.
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Free radicals, metals and antioxidants in oxidative stress-induced cancer
TL;DR: This review examines the evidence for involvement of the oxidative stress in the carcinogenesis process and the role of enzymatic and non-enzymatic antioxidants in the process of carcinogenesis as well as the antioxidant interactions with various regulatory factors.
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Role of oxygen radicals in DNA damage and cancer incidence
TL;DR: The epidemiological trials together with in vitro experiments suggest that the optimal approach is to reduce endogenous and exogenous sources of oxidative stress, rather than increase intake of anti-oxidants.
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Arsenic: toxicity, oxidative stress and human disease.
Klaudia Jomová,Zita Jenisová,Melánia Feszterová,Stanislav Baros,Líska J,Daniela Hudecová,Christopher J. Rhodes,Marian Valko +7 more
TL;DR: In this paper, the role of antioxidant defence systems against arsenic toxicity is discussed, and the role role of vitamin C (ascorbic acid), vitamin E (α-tocopherol), curcumin, glutathione and antioxidant enzymes such as superoxide dismutase, catalase, and peroxidase in their protective roles against arsenic-induced oxidative stress is also discussed.
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Targeting Free Radicals in Oxidative Stress-Related Human Diseases.
Patrik Poprac,Klaudia Jomová,Miriama Simunkova,Vojtech Kollar,Christopher J. Rhodes,Marian Valko +5 more
TL;DR: Metal chelation, based on the application of selective metal chelators or metal delivery, may induce neuroprotective signaling and represents a promising therapeutic strategy in cancer and AD.
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Redox- and non-redox-metal-induced formation of free radicals and their role in human disease.
TL;DR: Current views regarding the role of redox-active/inactive metal-induced formation of ROS, modifications to biomolecules in human disease such as cancer, cardiovascular disease, metabolic disease, Alzheimer's disease, Parkinson’s disease, renal disease, blood disorders and other disease are summarized.