C
Christopher M. Gomez
Researcher at University of Chicago
Publications - 211
Citations - 9119
Christopher M. Gomez is an academic researcher from University of Chicago. The author has contributed to research in topics: Spinocerebellar ataxia & Ataxia. The author has an hindex of 45, co-authored 197 publications receiving 8090 citations. Previous affiliations of Christopher M. Gomez include University of Alabama at Birmingham & University of Miami.
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Journal ArticleDOI
International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome
Paul Trouillas,Tetsuya Takayanagi,Mark Hallett,Robert D. Currier,S. H. Subramony,K. Wessel,Alan Bryer,Hans-Christoph Diener,S. Massaquoi,Christopher M. Gomez,Paula Coutinho,M. Ben Hamida,Giuseppe Campanella,Alessandro Filla,L. Schut,D. Timann,Jérôme Honnorat,Norbert Nighoghossian,Bala V. Manyam +18 more
TL;DR: The scale proposed involves a compartimentalized quantification of postural and stance disorders, limb ataxia, dysarthria and oculomotor disorders, in order that a subscore concerning these symptoms may be separately studied.
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Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy
James L. Urban,Vipin Kumar,Dwight H. Kono,Christopher M. Gomez,Suzanna J. Horvath,Julie Clayton,Dale G. Ando,Eli E. Sercarz,Leroy Hood +8 more
TL;DR: The anti-V beta 8 monoclonal antibody F23.1 was found to block completely recognition of the nonapeptide by V beta 8 TH cells in vitro and to reduce significantly the susceptibility of B10.PL mice to peptide-induced EAE.
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Measuring Friedreich ataxia: Interrater reliability of a neurologic rating scale
S. H. Subramony,W. May,David A. Lynch,Christopher M. Gomez,Kenneth H. Fischbeck,Mark Hallett,Paul Taylor,Robert B. Wilson,Tetsuo Ashizawa +8 more
TL;DR: The authors discuss the problems related to rating scales in the ataxias, report a neurologic rating scale for FA, and demonstrate acceptable interrater reliability of the instrument.
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Spinocerebellar ataxia type 6: Gaze‐evoked and vertical nystagmus, Purkinje cell degeneration, and variable age of onset
Christopher M. Gomez,Randall Thompson,Jason T. Gammack,Susan Perlman,William B. Dobyns,Charles L. Truwit,David S. Zee,H. Brent Clark,John H. Anderson +8 more
TL;DR: Clinical and quantitative measurement of extraocular movements demonstrated a characteristic pattern of ocular motor and vestibular abnormalities, including horizontal and vertical nystagmus and an abnormal vestibulo‐ocular reflex, which identifies a distinct phenotype associated with this newly recognized form of dominant SCA.
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Hereditary cerebellar ataxia progressively impairs force adaptation during goal-directed arm movements.
TL;DR: The failure to generalize learning suggests that cerebellar degeneration prevents the formation of an internal representation of the limb dynamics, which implies that progressive loss of Cerebellar function gradually impairs force adaptation.