C
Christos I. Gioumouxouzis
Researcher at Aristotle University of Thessaloniki
Publications - 13
Citations - 458
Christos I. Gioumouxouzis is an academic researcher from Aristotle University of Thessaloniki. The author has contributed to research in topics: Dosage form & Medicine. The author has an hindex of 6, co-authored 9 publications receiving 308 citations.
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Journal ArticleDOI
3D printed oral solid dosage forms containing hydrochlorothiazide for controlled drug delivery
Christos I. Gioumouxouzis,Orestis L. Katsamenis,Nikolaos Bouropoulos,Nikolaos Bouropoulos,Dimitrios G. Fatouros +4 more
TL;DR: In this article, an oral solid dosage form was created by Fused Deposition Modeling (FDM), using a custom built filament comprised of a water soluble polymer polyvinyl alcohol (PVA), mannitol and hydrochlorothiazide (HCTZ) as model drug and further co-formulated via Hot-Melt Extrusion (HME).
Journal ArticleDOI
A 3D printed bilayer oral solid dosage form combining metformin for prolonged and glimepiride for immediate drug delivery.
Christos I. Gioumouxouzis,Apostolos Baklavaridis,Orestis L. Katsamenis,Catherine K. Markopoulou,Nikolaos Bouropoulos,Dimitrios Tzetzis,Dimitrios G. Fatouros +6 more
TL;DR: The results from the current study emphasize the potentiality of 3D printing technology for tailor‐made solid dosage forms for combined pharmacotherapy, even at the cases when API's with different desirable release profiles are employed.
Journal ArticleDOI
Recent advances in pharmaceutical dosage forms and devices using additive manufacturing technologies.
TL;DR: An overview of the most recent advances in dosage forms and devices using additive manufacturing technologies, along with the regulatory landscape framing the development and safety requirements for 3D-printed drug products before entering the pharmaceutical market is provided.
Journal ArticleDOI
Fabrication of an osmotic 3D printed solid dosage form for controlled release of active pharmaceutical ingredients
Christos I. Gioumouxouzis,Emmanouil K. Tzimtzimis,Orestis L. Katsamenis,Anthi Dourou,Catherine K. Markopoulou,Nikolaos Bouropoulos,Dimitrios Tzetzis,Dimitrios G. Fatouros +7 more
TL;DR: The above results demonstrate the successful utilization of an FDM 3D printer in order to create osmotic 3D printed formulations exhibiting sustained and/or delayed release, that can be easily personalized containing API doses corresponding to each patient's specific needs.
Journal ArticleDOI
Controlled Release of 5-Fluorouracil from Alginate Beads Encapsulated in 3D Printed pH-Responsive Solid Dosage Forms.
Christos I. Gioumouxouzis,Aikaterini-Theodora Chatzitaki,Christina Karavasili,Orestis L. Katsamenis,Dimitrios Tzetzis,Emmanouela Mystiridou,Nikolaos Bouropoulos,Nikolaos Bouropoulos,Dimitrios G. Fatouros +8 more
TL;DR: The present study highlights the potential of additive manufacturing in fabricating controlled-release dosage forms rendering them pertinent formulations for further in vivo evaluation.