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Chunjuan Song

Researcher at University of Florida

Publications -  28
Citations -  6891

Chunjuan Song is an academic researcher from University of Florida. The author has contributed to research in topics: Oxidative stress & Autophagy. The author has an hindex of 18, co-authored 28 publications receiving 6114 citations. Previous affiliations of Chunjuan Song include University of Pennsylvania & Iowa State University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD.

Sayak K. Mitter, +11 more
- 30 Oct 2014 - 
TL;DR: It is confirmed that autophagy plays an important role in protection of the RPE against oxidative stress and lipofuscin accumulation and that impairment of autophagosome numbers and expression are likely to exacerbate oxidative Stress and contribute to the pathogenesis of AMD.
Journal ArticleDOI

Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration.

Chunjuan Song, +4 more
- 01 Apr 2010 - 
TL;DR: For the first time, it is demonstrated that exposure to the neurotoxic pesticide dieldrin induces acetylation of core histones because of proteasomal dysfunction and that hyperacetylation plays a key role in dopaminergic neuronal degeneration after exposure of d yieldrin.
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Oral Delivery of Angiotensin-Converting Enzyme 2 and Angiotensin-(1-7) Bioencapsulated in Plant Cells Attenuates Pulmonary Hypertension

Vinayak Shenoy, +13 more
- 01 Dec 2014 - 
TL;DR: This study provides proof-of-concept for a novel low-cost oral ACE2 or Ang-(1-7) delivery system using transplastomic technology for pulmonary disease therapeutics and prevents the development of monocrotaline-induced PH and improved associated cardiopulmonary pathophysiology.
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Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells.

Vellareddy Anantharam, +4 more
- 01 Sep 2007 - 
TL;DR: It is shown for the first time that intracellular ROS generated by NAPDH oxidase are present within the mesencephalic neuronal cells, and are a key determinant of MPP+-mediated dopaminergic degeneration in in vitro models of dopaminerg degeneration.