C
Chunmei Zhang
Researcher at Chinese Ministry of Education
Publications - 15
Citations - 180
Chunmei Zhang is an academic researcher from Chinese Ministry of Education. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 8 publications receiving 67 citations.
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Journal ArticleDOI
Adipose HuR protects against diet-induced obesity and insulin resistance.
Jingyuan Li,Li Gong,Shaozhuang Liu,Yujie Zhang,Chunmei Zhang,Mi Tian,Huixia Lu,Peili Bu,Jianmin Yang,Chang-Han Ouyang,Xiuxin Jiang,Jiliang Wu,Yun Zhang,Qing Min,Cheng Zhang,Wencheng Zhang,Wencheng Zhang +16 more
TL;DR: Investigating the role of adipose HuR in adipose tissue finds that it protects mice from diet-induced obesity, prevents adipocyte hypertrophy, and promotes lipolysis, which may at least in part be due to HuR-dependent ATGL mRNA stability regulation demonstrated in-vitro.
Journal Article
SIRT3 attenuates AngII-induced cardiac fibrosis by inhibiting myofibroblasts transdifferentiation via STAT3-NFATc2 pathway.
TL;DR: SIRT3 can protect against cardiac fibrosis by inhibiting myofibroblasts transdifferentiation via the STAT3-NFATc2 signaling pathway, and it is demonstrated that it directly binds to and deacetylates STAT3 to inhibit its activity.
Journal ArticleDOI
Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3
Chunmei Zhang,Mengying Suo,Lingxin Liu,Yan Qi,Chen Zhang,Lin Xie,Xuehui Zheng,Chang Ma,Jingyuan Li,Jianmin Yang,Peili Bu +10 more
TL;DR: In this article, the authors investigated the protection and mechanisms of melatonin against contrast-induced acute kidney injury (CI-AKI) in a mouse model and NRK-52E cells, and found that melatonin significantly increased the expression of Sirt3 and decreased the ac-SOD2 K68 level.
Journal ArticleDOI
Sirt3 promotes sensitivity to sunitinib-induced cardiotoxicity via inhibition of GTSP1/JNK/autophagy pathway in vivo and in vitro.
Yi Yang,Na Li,Tongshuai Chen,Chunmei Zhang,Jingyuan Li,Lingxin Liu,Yan Qi,Xuehui Zheng,Chen Zhang,Peili Bu +9 more
TL;DR: It is demonstrated that Sirt3 promotes sensitivity to sunitinib-induced cardiotoxicity via GSTP1/JNK/autophagy pathway and might be a potential target for developing cardioprotective therapies for sunit inib-receiving patients.
Journal ArticleDOI
Lcz696 Alleviates Myocardial Fibrosis After Myocardial Infarction Through the sFRP-1/Wnt/β-Catenin Signaling Pathway.
TL;DR: In this article, the authors investigated the effect of angiotensin receptor-neprilysin inhibitor (ARNI) on the Wnt/β-catenin signaling pathway after myocardial infarction (MI).