Cirandur Suresh Reddy

TL;DR: These studies revealed that 7-hydroxycoumarin derivatives caused an increased inhibition in growth of inflamed macrophages in a concentration-dependent manner with an IC50 of 78, 63, and 50 μM, suggesting that there are hydrophobic interactions when coumarin derivative-inspired drugs bind to HSA.

TL;DR: The BB resistance gene present in the O. nivara accession was identified to be novel based on its unique map location on chromosome 7 and wider spectrum of BB resistance; this gene has been named Xa33.

TL;DR: The AgNps showed potential activity against all of the bacterial strains and fungal colonies, indicating that R. nasutus has the potential to be used in the development of value-added products in the biomedical and nanotechnology-based industries.

TL;DR: In insights into designing of the new inspired coumarin derivatives as therapeutic agents against many life threatening diseases, the binding of synthesized cou marin derivatives with human serum albumin (HSA) at physiological pH 7.2 is studied.

TL;DR: A mild and efficient Pd-catalyzed arylative domino carbocyclization of cyclohexadienone-containing 1,6-enynes is described, tolerates a variety of functionalized boronic acids to afford a cis-fused bicyclic framework containing an α,β-unsaturated ketone with excellent regio- and diastereoselectivity in good yields.