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Claes-Göran Löfdahl

Researcher at Lund University

Publications -  190
Citations -  11180

Claes-Göran Löfdahl is an academic researcher from Lund University. The author has contributed to research in topics: COPD & Formoterol. The author has an hindex of 53, co-authored 188 publications receiving 10645 citations. Previous affiliations of Claes-Göran Löfdahl include Sahlgrenska University Hospital & Astra.

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Journal ArticleDOI

Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group

TL;DR: In patients who have persistent symptoms of asthma despite treatment with inhaled glucocorticoids, the addition of formoterol to budesonid therapy or the use of a higher dose of budesonide may be beneficial.
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Long-Term Treatment with Inhaled Budesonide in Persons with Mild Chronic Obstructive Pulmonary Disease Who Continue Smoking

TL;DR: A double-blind, placebo-controlled study evaluated the effect of the inhaled glucocorticoid budesonide in subjects with mild COPD who continued smoking and found that the FEV1 improved at the rate of 17 ml per year in the budesonid group, which was higher than the predicted value.
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Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European Respiratory Society

TL;DR: A Task Force supported by the European Respiratory Society was set up in 1997 in order to address the major issues relevant to difficult/therapy-resistant asthma as mentioned in this paper, and the Task Force also concerned itself with defining the areas of research necessary to bring about a greater understanding of the causes of difficult asthma and novel treatments.
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Exacerbations of asthma: a descriptive study of 425 severe exacerbations. The FACET International Study Group.

TL;DR: Exacerbations identified by the need for oral corticosteroids were associated with more symptoms and smaller changes in PEF than those identified on the basis of PEF criteria, and female sex was the main patient characteristic associated with an increased risk of having a severe exacerbation.
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Health-related quality of life is related to COPD disease severity

TL;DR: The results show that HRQL in COPD deteriorates with disease severity and with age, and a relationship between HRQL and disease severity obtained by lung function is shown.