C
Claire Corot
Researcher at Guerbet
Publications - 171
Citations - 8605
Claire Corot is an academic researcher from Guerbet. The author has contributed to research in topics: Gadolinium & Blood pool agent. The author has an hindex of 45, co-authored 170 publications receiving 8046 citations.
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Recent advances in iron oxide nanocrystal technology for medical imaging
TL;DR: Stem cell migration and immune cell trafficking, as well as targeted iron oxide nanoparticles for molecular imaging studies, are at the stage of proof of concept, mainly in animal models.
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Macrophage endocytosis of superparamagnetic iron oxide nanoparticles: mechanisms and comparison of ferumoxides and ferumoxtran-10.
Isabelle Raynal,Philippe Prigent,Sophie Peyramaure,Abderrahim Najid,Cécile Rebuzzi,Claire Corot +5 more
TL;DR: Competition experiments indicate that the cellular uptake of Ferumoxides involves scavenger receptor SR-A-mediated endocytosis and confirms that macrophage uptake of iron oxide nanoparticles depends mainly on the size of these contrast agents.
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Clinical and biological consequences of transmetallation induced by contrast agents for magnetic resonance imaging: a review
TL;DR: There is increasing evidence that transmetallation can be found in vivo, in the case of certain CAs (especially linear chelates), with body cations such as zinc, calcium or iron.
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Efficiency, thermodynamic and kinetic stability of marketed gadolinium chelates and their possible clinical consequences: a critical review
TL;DR: A high kinetic stability provided by the macrocyclic structure combined with a high thermodynamic stability (reinforced by ionicity for macro cyclic chelates) will minimize the amount of free gadolinium released in tissue parenchymas.
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MRI of Tumor-Associated Macrophages with Clinically Applicable Iron Oxide Nanoparticles
Heike E. Daldrup-Link,Daniel Golovko,Brian Ruffell,David G. DeNardo,Rosalinda Castaneda,Celina Ansari,Jianghong Rao,Grigory Tikhomirov,Michael F. Wendland,Claire Corot,Lisa M. Coussens +10 more
TL;DR: T tumor enhancement with clinically applicable iron oxide nanoparticles may serve as a new biomarker for long-term prognosis, related treatment decisions, and the evaluation of new immune-targeted therapies.