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Clarissa Gerhäuser

Researcher at German Cancer Research Center

Publications -  114
Citations -  10244

Clarissa Gerhäuser is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: DNA methylation & Xanthohumol. The author has an hindex of 46, co-authored 113 publications receiving 8682 citations. Previous affiliations of Clarissa Gerhäuser include University of Illinois at Urbana–Champaign & University of Illinois at Chicago.

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Pan-cancer analysis of whole genomes

Peter J. Campbell, +1332 more
- 06 Feb 2020 - 
TL;DR: The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.
Journal ArticleDOI

Nuclear Factor κB Is a Molecular Target for Sulforaphane-mediated Anti-inflammatory Mechanisms

TL;DR: A potent decrease in lipopolysaccharide (LPS)-induced secretion of pro-inflammatory and pro-carcinogenic signaling factors in cultured Raw 264.7 macrophages after SFN treatment is reported, providing novel evidence that anti-inflammatory mechanisms contribute to sulforaphane-mediated cancer chemoprevention.
Journal Article

Cancer chemopreventive activity of Xanthohumol, a natural product derived from hop.

TL;DR: Together, the data provide evidence for the potential application of XN as a novel, readily available chemopreventive agent, and clinical investigations are warranted once efficacy and safety in animal models have been established.
Journal ArticleDOI

Beer constituents as potential cancer chemopreventive agents

TL;DR: Chemopreventive activities observed with these compounds relevant to inhibition of carcinogenesis at the initiation, promotion and progression phases, as well as results from in vivo studies on metabolism, bioavailability and efficacy are summarised in this review.