Claude Bouchard

TL;DR: MC4R andMC5R exibit evidence of linkage or association with obesity phenotypes, but this evidence is strongest for MC5R.

TL;DR: In this paper, the authors conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716 individuals to increase the understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk.

TL;DR: It is suggested that physical activity level is characterized by a significant degree of familial resemblance, and that inactivity has a slightly higher heritability level than moderate to strenuous physical activity or total physical activity phenotypes.

TL;DR: Women generally displayed a more favourable risk profile than men which included higher plasma HDL2-cholesterol and lower plasma insulin, apolipoprotein B and triglyceride levels, and gender differences for plasma concentrations of HDL-ch cholesterol, HDL2 -cholesterol as well as the ratio of cholesterol/total cholesterol remained significantly higher in women than in men.

TL;DR: The exercise program significantly lowered the adiposity of men and increased adipocyte epinephrine maximal stimulated lipolysis in women and men, respectively, and in both sexes, a significant increase in ESL was observed after training.