Author
Claudio Pettinari
Other affiliations: Sapienza University of Rome, University of Turin, University of South Carolina ...read more
Bio: Claudio Pettinari is an academic researcher from University of Camerino. The author has contributed to research in topics: Denticity & Ligand. The author has an hindex of 50, co-authored 407 publications receiving 10768 citations. Previous affiliations of Claudio Pettinari include Sapienza University of Rome & University of Turin.
Papers published on a yearly basis
Papers
More filters
TL;DR: In this paper, a comprehensive surwey of the tris(pyrazolyl)alkanes coordination chemistry, based on the nature of the metal, is presented, together with the main synthetic methods and spectroscopic and structural features of this important class of ligands.
371 citations
Book•
01 Jan 2008
TL;DR: In this article, Scorpionates based on Thioimidazolones as Sulfur Donors, Thioethers and Dialkyl Phosphines as Donors Applications of Scorpionate Ligands
Abstract: Homoscorpionates -- First Generation Homoscorpionates -- Second Generation Heteroscorpionates, RR'Bpx Scorpionates Based on Thioimidazolones as Sulfur Donors Scorpionates Based on Thioethers as Sulfur Donors Scorpionates Based on Diaryl or Dialkyl Phosphines as Donors Applications of Scorpionate Ligands.
278 citations
TL;DR: In this paper, a review summarizes the literature on 4-acyl-5-pyrazolone ligands, their synthesis, characterization and coordination chemistry toward main group, transition, lanthanide and actinide metals and relevant applications of their metal complexes.
244 citations
TL;DR: In this article, a survey on transition metal containing coordination polymers and metal-organic frameworks (MOFs) with poly(pyrazole)-and poly (pyrazolate)-based ligands is presented, where up to three N-donor heterocyclic rings are organized on rigid or flexible cores.
201 citations
TL;DR: The in vitro antiproliferative activity of the title compound on five tumor cell lines shows preference for the colon-rectal tumor HCT116, IC(50) = 13.98 μM, followed by breast MCF7 and ovarian A2780 cell lines; human glioblastoma U-87 and lung carcinoma A549 are less sensitive.
Abstract: The in vitro antiproliferative activity of the title compound on five tumor cell lines shows preference for the colon–rectal tumor HCT116, IC50 = 13.98 μM, followed by breast MCF7 (19.58 μM) and ovarian A2780 (23.38 μM) cell lines; human glioblastoma U-87 and lung carcinoma A549 are less sensitive. A commercial curcumin reagent, also containing demethoxy and bis-demethoxy curcumin, was used to synthesize the title compound, and so (p-cymene)Ru(demethoxy-curcuminato)chloro was also isolated and chemically characterized. The crystal structure of the title compound shows (1) the chlorine atom linking two neighboring complexes through H-bonds with two O(hydroxyl), forming an infinite two-step network; (2) significant twist in the curcuminato, 20° between the planes of the two phenyl rings. This was also seen in the docking of the Ru-complex onto a rich guanine B-DNA decamer, where a Ru–N7(guanine) interaction is detected. This Ru–N7(guanine) interaction is also seen with ESI-MS on a Ru-complex-guanosine deriv...
195 citations
Cited by
More filters
01 Dec 1991
TL;DR: In this article, self-assembly is defined as the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds.
Abstract: Molecular self-assembly is the spontaneous association of molecules under equilibrium conditions into stable, structurally well-defined aggregates joined by noncovalent bonds. Molecular self-assembly is ubiquitous in biological systems and underlies the formation of a wide variety of complex biological structures. Understanding self-assembly and the associated noncovalent interactions that connect complementary interacting molecular surfaces in biological aggregates is a central concern in structural biochemistry. Self-assembly is also emerging as a new strategy in chemical synthesis, with the potential of generating nonbiological structures with dimensions of 1 to 10(2) nanometers (with molecular weights of 10(4) to 10(10) daltons). Structures in the upper part of this range of sizes are presently inaccessible through chemical synthesis, and the ability to prepare them would open a route to structures comparable in size (and perhaps complementary in function) to those that can be prepared by microlithography and other techniques of microfabrication.
2,591 citations
[...]
TL;DR: The specific advantages brought up by a design based on the use of the halogen bond will be demonstrated in quite different fields spanning from material sciences to biomolecular recognition and drug design.
Abstract: The halogen bond occurs when there is evidence of a net attractive interaction between an electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic region in another, or the same, molecular entity. In this fairly extensive review, after a brief history of the interaction, we will provide the reader with a snapshot of where the research on the halogen bond is now, and, perhaps, where it is going. The specific advantages brought up by a design based on the use of the halogen bond will be demonstrated in quite different fields spanning from material sciences to biomolecular recognition and drug design.
2,582 citations