C
Cliff Han
Researcher at Los Alamos National Laboratory
Publications - 280
Citations - 16113
Cliff Han is an academic researcher from Los Alamos National Laboratory. The author has contributed to research in topics: Genome & Whole genome sequencing. The author has an hindex of 51, co-authored 280 publications receiving 14665 citations. Previous affiliations of Cliff Han include Oak Ridge National Laboratory & Joint Genome Institute.
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Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina).
Diego Martinez,Diego Martinez,Randy M. Berka,Bernard Henrissat,Markku Saloheimo,Mikko Arvas,Scott E. Baker,Jarod Chapman,Olga Chertkov,Pedro M. Coutinho,Dan Cullen,Etienne Danchin,Igor V. Grigoriev,Paul Harris,Melissa Jackson,Christian P. Kubicek,Cliff Han,Isaac Ho,Luis F. Larrondo,Alfredo Lopez de Leon,Jon K. Magnuson,Sandy Merino,Monica Misra,Beth Nelson,Nicholas H. Putnam,Barbara Robbertse,Asaf Salamov,Monika Schmoll,Astrid Terry,Nina Thayer,Ann Westerholm-Parvinen,Conrad L. Schoch,Jian Yao,Ravi D. Barabote,Mary Anne Nelson,Chris Detter,David Bruce,Cheryl R. Kuske,Gary Xie,Paul G. Richardson,Daniel S. Rokhsar,Susan Lucas,Edward M. Rubin,Nigel Dunn-Coleman,Michael Ward,Thomas Brettin +45 more
TL;DR: This work assembled 89 scaffolds to generate 34 Mbp of nearly contiguous T. reesei genome sequence comprising 9,129 predicted gene models, providing a roadmap for constructing enhanced T.Reesei strains for industrial applications such as biofuel production.
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A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea.
Dongying Wu,Dongying Wu,Philip Hugenholtz,Konstantinos Mavromatis,Rüdiger Pukall,Eileen Dalin,Natalia Ivanova,Victor Kunin,Lynne Goodwin,Martin Wu,Brian J. Tindall,Sean D. Hooper,Amrita Pati,Athanasios Lykidis,Stefan Spring,Iain Anderson,Patrik D'haeseleer,Patrik D'haeseleer,Adam Zemla,Mitchell Singer,Alla Lapidus,Matt Nolan,Alex Copeland,Cliff Han,Feng Chen,Jan Fang Cheng,Susan Lucas,Cheryl A. Kerfeld,Elke Lang,Sabine Gronow,Patrick S. G. Chain,Patrick S. G. Chain,David Bruce,Edward M. Rubin,Nikos C. Kyrpides,Hans-Peter Klenk,Jonathan A. Eisen,Jonathan A. Eisen +37 more
TL;DR: The results strongly support the need for systematic ‘phylogenomic’ efforts to compile a phylogeny-driven ‘Genomic Encyclopedia of Bacteria and Archaea’ in order to derive maximum knowledge from existing microbial genome data as well as from genome sequences to come.
Journal ArticleDOI
Three Genomes from the Phylum Acidobacteria Provide Insight into the Lifestyles of These Microorganisms in Soils
Naomi L. Ward,Jean F. Challacombe,Jean F. Challacombe,Peter H. Janssen,Peter H. Janssen,Bernard Henrissat,Pedro M. Coutinho,Martin Wu,Gary Xie,Gary Xie,Daniel H. Haft,Michelle Sait,Jonathan H. Badger,Ravi D. Barabote,Ravi D. Barabote,Brent Bradley,Thomas Brettin,Thomas Brettin,Lauren M. Brinkac,David Bruce,David Bruce,Todd Creasy,Sean C. Daugherty,Tanja M. Davidsen,Robert T. DeBoy,J. Chris Detter,J. Chris Detter,Robert J. Dodson,A. Scott Durkin,Anuradha Ganapathy,Michelle Gwinn-Giglio,Cliff Han,Cliff Han,Hoda Khouri,Hajnalka Kiss,Hajnalka Kiss,Sagar Kothari,Ramana Madupu,Karen E. Nelson,William C. Nelson,Ian T. Paulsen,Kevin Penn,Qinghu Ren,M. J. Rosovitz,Jeremy D. Selengut,Susmita Shrivastava,Steven A. Sullivan,Roxanne Tapia,Roxanne Tapia,L. Sue Thompson,L. Sue Thompson,Kisha Watkins,Qi Yang,Chunhui Yu,Nikhat Zafar,Liwei Zhou,Cheryl R. Kuske +56 more
TL;DR: Combining the genomic evidence with available culture traits, it is postulate that cells of these isolates are long-lived, divide slowly, exhibit slow metabolic rates under low-nutrient conditions, and are well equipped to tolerate fluctuations in soil hydration.
Journal ArticleDOI
Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing
Patrick M. Shih,Patrick M. Shih,Dongying Wu,Amel Latifi,Seth D. Axen,David P. Fewer,Emmanuel Talla,Alexandra Calteau,Fei Cai,Nicole Tandeau de Marsac,Rosmarie Rippka,Michael Herdman,Kaarina Sivonen,Thérèse Coursin,Thierry Laurent,Lynne Goodwin,Matt Nolan,Karen W. Davenport,Cliff Han,Edward M. Rubin,Jonathan A. Eisen,Tanja Woyke,Muriel Gugger,Cheryl A. Kerfeld,Cheryl A. Kerfeld +24 more
TL;DR: This phylum-wide study highlights the benefits of diversity-driven genome sequencing, identifying more than 21,000 cyanobacterial proteins with no detectable similarity to known proteins, and foregrounds the diversity of light-harvesting proteins and gene clusters for secondary metabolite biosynthesis.
Journal ArticleDOI
The genomic basis of trophic strategy in marine bacteria.
Federico M. Lauro,Diane McDougald,Torsten Thomas,Timothy J. Williams,Suhelen Egan,Scott A. Rice,Matthew Z. DeMaere,Lily Ting,Haluk Ertan,Haluk Ertan,Justin Johnson,Steven Ferriera,Alla Lapidus,Iain Anderson,Nikos C. Kyrpides,A. Christine Munk,Chris Detter,Cliff Han,Mark V. Brown,Frank T. Robb,Staffan Kjelleberg,Ricardo Cavicchioli +21 more
TL;DR: This work compares the genome sequences of two bacteria, Photobacterium angustum S14 and Sphingopyxis alaskensis RB2256, that serve as useful model organisms for copiotrophic and oligotrophic modes of life and relates the genomic features to trophic strategy for these organisms and defines their molecular mechanisms of adaptation.