C
Conor Burke
Researcher at Connolly Hospital Blanchardstown
Publications - 67
Citations - 3268
Conor Burke is an academic researcher from Connolly Hospital Blanchardstown. The author has contributed to research in topics: Asthma & T cell. The author has an hindex of 26, co-authored 65 publications receiving 2968 citations. Previous affiliations of Conor Burke include Memorial Hospital of South Bend.
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Journal ArticleDOI
Disordered Microbial Communities in Asthmatic Airways
Markus Hilty,Conor Burke,Helder Pedro,Helder Pedro,Paul Cardenas,Andrew Bush,Cara Bossley,Jane C. Davies,Aaron Ervine,Len Poulter,Lior Pachter,Miriam F. Moffatt,William O.C.M. Cookson +12 more
TL;DR: The results show the bronchial tree to contain a characteristic microbiota, and suggest that this microbiota is disturbed in asthmatic airways.
Journal ArticleDOI
Activated, Cytotoxic CD8+ T Lymphocytes Contribute to the Pathology of Asthma Death
S. O'sullivan,Liam Cormican,John Faul,S. Ichinohe,Sebastian L. Johnston,Conor Burke,L. W. Poulter +6 more
TL;DR: Novel evidence is provided of an aberrant CD8(+) T-cell population, possibly in response to viral infection in subjects who die of acute asthma, that is higher in the AD group than the control group.
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Lung immunopathology in cases of sudden asthma death
TL;DR: Sudden asphyxic asthma is associated with inflammatory infiltrates both of proximal and distal lung tissues, and this infiltrate contains large numbers of CD8+ T-cells, suggesting distinct qualitative as well as quantitative characteristics in the immunopathology of sudden asthma death.
Journal ArticleDOI
Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood
Unnur S. Bjornsdottir,Stephen T. Holgate,Padmalatha S. Reddy,Andrew A. Hill,Charlotte Marie McKee,Cristina Ileana Csimma,Amy A Weaver,Holly M. Legault,Clayton Small,Renee Ramsey,Debra K. Ellis,Conor Burke,Philip J. Thompson,Peter H. Howarth,Andrew J. Wardlaw,Phillip G. Bardin,David I. Bernstein,Louis Irving,Geoffrey L. Chupp,George W. Bensch,Gregory W. Bensch,Jon E. Stahlman,Monroe Karetzky,James W. Baker,Rachel L. Miller,Brad H. Goodman,Donald G. Raible,Samuel J. Goldman,Douglas K. Miller,John Louis Ryan,Andrew J. Dorner,Immermann Frederick,Margot O'Toole +32 more
TL;DR: This study has shown that analysis of PBMCs reveals systemic changes accompanying asthma exacerbation and has laid the foundation for future comparative studies usingPBMCs.
Journal ArticleDOI
A comparative evaluation of propofol and midazolam as sedative agents in fiberoptic bronchoscopy.
TL;DR: It is concluded that propofol is a useful sedating agent in fiberoptic bronchoscopy with similar efficacy to midazolam but with a faster onset of action and a more rapid recovery, which represent significant advantages for day-case procedures.