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Constance R. Chu
Researcher at Stanford University
Publications - 147
Citations - 9211
Constance R. Chu is an academic researcher from Stanford University. The author has contributed to research in topics: Cartilage & Osteoarthritis. The author has an hindex of 52, co-authored 138 publications receiving 8001 citations. Previous affiliations of Constance R. Chu include United States Department of Veterans Affairs & University of Pittsburgh.
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Injectable In Situ Forming Biodegradable Chitosan-Hyaluronic acid Based Hydrogels for Cartilage Tissue Engineering
TL;DR: A new class of biocompatible and biodegradable composite hydrogels derived from water-soluble chitosan and oxidized hyaluronic acid upon mixing, without the addition of a chemical crosslinking agent is reported.
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Animal models for cartilage regeneration and repair.
TL;DR: This review focuses on the use of animal models for the study of the repair and regeneration of focal cartilage defects, including murine, lapine, canine, caprine, porcine, and equine models.
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The Clinical Use of Human Culture–Expanded Autologous Bone Marrow Mesenchymal Stem Cells Transplanted on Platelet-Rich Fibrin Glue in the Treatment of Articular Cartilage Defects: A Pilot Study and Preliminary Results
Amgad M. Haleem,Abdel Aziz El Singergy,Dina Sabry,Hazem Atta,Laila A. Rashed,Constance R. Chu,Mohammed T. El Shewy,Akram Azzam,Mohammed Talaat Abdel Aziz +8 more
TL;DR: Testing the hypothesis that platelet-rich fibrin glue can be used clinically as a scaffold to deliver autologous culture-expanded bone marrow mesenchymal stem cells (BM-MSCs) for cartilage repair and to report clinical results 1 y after implantation of MSCs PR-FG found it to be effective.
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Articular cartilage repair using allogeneic perichondrocyteseeded biodegradable porous polylactic acid (PLA): A tissue‐engineering study
Constance R. Chu,Richard D. Coutts,Makoto Yoshioka,Frederick L. Harwood,Anna Z. Monosov,David Amiel +5 more
TL;DR: Results suggest that scaffolds composed of porous D,D-L,L-polylactic acid support the growth of cartilaginous repair tissue and are compatible with both in vitro and in vivo survival of chondrogenic cells.
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Articular cartilage transplantation. Clinical results in the knee.
TL;DR: The results support the use of fresh osteochondral shell allograft transplantation for the treatment of large, full thickness articular cartilage defects to the medial or lateral femoral condyles and to the patella.