Author
Contzen Pereira
Other affiliations: Jawaharlal Nehru Centre for Advanced Scientific Research
Bio: Contzen Pereira is an academic researcher from St. Xavier's College-Autonomous, Mumbai. The author has contributed to research in topics: Consciousness & Normal diet. The author has an hindex of 10, co-authored 42 publications receiving 344 citations. Previous affiliations of Contzen Pereira include Jawaharlal Nehru Centre for Advanced Scientific Research.
Topics: Consciousness, Normal diet, Corn oil, Diethyl phthalate, Achatina
Papers
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TL;DR: It is evident from this study that treatment with higher concentrations of DEP results in mitochondrial proliferation as well as accumulation of glycogen, cholesterol and triglycerides within the liver, but exposure to lower concentrations for longer periods results in increase in peroxisome numbers leading to severe hepatocellular changes.
56 citations
TL;DR: It is concluded that combined administration of Clophen A60 and DEP shows an enhanced toxic effect on adrenal glands of F1-generation male and female rats, but the effect is much more marked in the thyroglobulin and fibrosis of the interfollicular epithelium.
37 citations
TL;DR: It can be concluded from this study, that continuous exposure through food, gestation and lactation over three generation's inspite of dose reduction of DEP leads to an enhanced toxic effect in the latter generations.
24 citations
TL;DR: A significant dose dependent increase was observed in serum acid phosphatase (ACP), serum and liver triglycerides levels showed a significant increase only in the high-dose treated group, and significant dose-dependent increase in serum aspartate and alanine aminotransferase and liver glycogen was observed.
21 citations
TL;DR: A synergistic interactive toxic effect of PCB and DEP was evident in both male and female pups in the following study, with significant increase in liver and serum lactate dehydrogenase (LDH) and acid phosphatase (ACP) activity and significant decrease in liver ALP.
18 citations
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1,087 citations
447 citations
TL;DR: Behavior domains adversely associated with prenatal exposure to LMW phthalates in this study are commonly found to be affected in children clinically diagnosed with conduct or attention deficit hyperactivity disorders.
Abstract: BackgroundExperimental and observational studies have reported biological consequences of phthalate exposure relevant to neurodevelopment.ObjectiveOur goal was to examine the association of prenata...
384 citations
TL;DR: Books and internet are the recommended media to help you improving your quality and performance.
Abstract: Inevitably, reading is one of the requirements to be undergone. To improve the performance and quality, someone needs to have something new every day. It will suggest you to have more inspirations, then. However, the needs of inspirations will make you searching for some sources. Even from the other people experience, internet, and many books. Books and internet are the recommended media to help you improving your quality and performance.
377 citations
TL;DR: Prenatal phthalate exposure was associated with childhood social impairment in a multiethnic urban population and the previous finding of atypical neonatal and early childhood behaviors in relation to prenatal phthalates was extended.
Abstract: Prenatal exposure to endocrine disruptors has the potential to impact early brain development. Neurodevelopmental toxicity in utero may manifest as psychosocial deficits later in childhood. This study investigates prenatal exposure to two ubiquitous endocrine disruptors, the phthalate esters and bisphenol A (BPA), and social behavior in a sample of adolescent inner-city children. Third trimester urines of women enrolled in the Mount Sinai Children's Environmental Health Study between 1998 and 2002 (n = 404) were analyzed for phthalate metabolites and BPA. Mother-child pairs were asked to return for a follow-up assessment when the child was between the ages of 7 to 9 years. At this visit, mothers completed the Social Responsiveness Scale (SRS) (n = 137), a quantitative scale for measuring the severity of social impairment related to Autistic Spectrum Disorders (ASD) in the general population. In adjusted general linear models increasing log-transformed low molecular weight phthalate (LMW) metabolite concentrations were associated with greater social deficits (β = 1.53, 95% CI 0.25-2.8). Among the subscales, LMWP were also associated with poorer Social Cognition (β = 1.40, 95% CI 0.1-2.7); Social Communication (β = 1.86, 95% CI 0.5-3.2) and Social Awareness (β = 1.25, 95% CI 0.1-2.4), but not for Autistic Mannerisms or Social Motivation. No significant association with BPA was found (β = 1.18, 95% CI: -0.75, 3.11). Prenatal phthalate exposure was associated with childhood social impairment in a multiethnic urban population. Even mild degrees of impaired social functioning in otherwise healthy individuals can have very important adverse effects over a child's lifetime. These results extend our previous finding of atypical neonatal and early childhood behaviors in relation to prenatal phthalate exposure.
352 citations