C
Cristina Chimenti
Researcher at Sapienza University of Rome
Publications - 188
Citations - 8757
Cristina Chimenti is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Cardiomyopathy & Myocarditis. The author has an hindex of 36, co-authored 149 publications receiving 7658 citations. Previous affiliations of Cristina Chimenti include The Catholic University of America & New York Medical College.
Papers
More filters
Journal ArticleDOI
Histological Substrate of Atrial Biopsies in Patients With Lone Atrial Fibrillation
Andrea Frustaci,Cristina Chimenti,Fulvio Bellocci,Emanuela Morgante,Matteo A. Russo,Attilio Maseri +5 more
TL;DR: Abnormal atrial histology was uniformly found in multiple biopsy specimens in all patients with LAF and was compatible with a diagnosis of myocarditis in 66% of patients and of noninflammatory localized cardiomyopathy in 17% and was represented by patchy fibrosis in 17%.
Journal ArticleDOI
Myocardial Cell Death in Human Diabetes
Andrea Frustaci,Jan Kajstura,Cristina Chimenti,Igor Jakoniuk,Annarosa Leri,Attilio Maseri,Bernardo Nadal-Ginard,Piero Anversa +7 more
TL;DR: Local increases in Ang II with Diabetes and with diabetes and hypertension may enhance oxidative damage, activating cardiac cell apoptosis and necrosis, in cells containing this modified amino acid.
Journal ArticleDOI
Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study
TL;DR: Data confirm the efficacy of immunosuppression in virus-negative inflammatory cardiomyopathy and lack of response in 12% of cases suggests the presence of not screened viruses or mechanisms of damage and inflammation not susceptible to immunOSuppression.
Journal ArticleDOI
Immunosuppressive Therapy for Active Lymphocytic Myocarditis: Virological and Immunologic Profile of Responders Versus Nonresponders
Andrea Frustaci,Cristina Chimenti,Fiorella Calabrese,Maurizio Pieroni,Gaetano Thiene,Attilio Maseri +5 more
TL;DR: In patients with active lymphocytic myocarditis, those with circulating cardiac autoantibodies and no viral genome in the myocardium are the most likely to benefit from immunosuppression.
Journal ArticleDOI
Reciprocal Regulation of MicroRNA-1 and Insulin-Like Growth Factor-1 Signal Transduction Cascade in Cardiac and Skeletal Muscle in Physiological and Pathological Conditions
Leonardo Elia,Riccardo Contu,Manuela Quintavalle,Francesca Varrone,Cristina Chimenti,Matteo Antonio Russo,Vincenzo Cimino,Laura De Marinis,Andrea Frustaci,Daniele Catalucci,Gianluigi Condorelli +10 more
TL;DR: A critical role is revealed in mediating the effects of the IGF-1 pathway and a feedback loop between miR-1 expression and theIGF-1 signal transduction cascade is demonstrated.