C
Cristina Grange
Researcher at University of Turin
Publications - 95
Citations - 7598
Cristina Grange is an academic researcher from University of Turin. The author has contributed to research in topics: Mesenchymal stem cell & Stem cell. The author has an hindex of 32, co-authored 82 publications receiving 6303 citations.
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Journal ArticleDOI
Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury
Stefania Bruno,Cristina Grange,Maria Chiara Deregibus,Raffaele A. Calogero,Silvia Saviozzi,Federica Collino,Laura Morando,Alessandro Busca,Michele Falda,Benedetta Bussolati,Ciro Tetta,Giovanni Camussi +11 more
TL;DR: It is found that microvesicles derived from human bone marrow MSCs stimulated proliferation in vitro and conferred resistance of tubular epithelial cells to apoptosis, suggesting RNA-dependent biologic effects.
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Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche
Cristina Grange,Marta Tapparo,Federica Collino,Loriana Vitillo,Christian Damasco,Maria Chiara Deregibus,Ciro Tetta,Benedetta Bussolati,Giovanni Camussi +8 more
TL;DR: This work reports that a subset of tumor-initiating cells expressing the mesenchymal stem cell marker CD105 in human renal cell carcinoma releases MVs that trigger angiogenesis and promote the formation of a premetastatic niche.
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Isolation of Renal Progenitor Cells from Adult Human Kidney
Benedetta Bussolati,Stefania Bruno,Cristina Grange,Stefano Buttiglieri,Maria Chiara Deregibus,Dario Cantino,Giovanni Camussi +6 more
TL;DR: It is proposed that CD133+ cells from kidney represent a multipotent adult resident stem cell population that may contribute to the repair of renal injury.
Journal ArticleDOI
Microvesicles Derived from Mesenchymal Stem Cells Enhance Survival in a Lethal Model of Acute Kidney Injury
Stefania Bruno,Cristina Grange,Federica Collino,Maria Chiara Deregibus,Vincenzo Cantaluppi,Luigi Biancone,Ciro Tetta,Giovanni Camussi +7 more
TL;DR: MVs released from MSCs were found to exert a pro-survival effect on renal cells in vitro and in vivo, suggesting that MVs may contribute to renal protection conferred by M SCs.
Journal Article
Exosome/microvesicle-mediated epigenetic reprogramming of cells
Giovanni Camussi,Maria-Chiara Deregibus,Stefania Bruno,Cristina Grange,Valentina Fonsato,Ciro Tetta +5 more
TL;DR: This finding suggests that tumor and stromal cells may talk each other via MVs to establish a favorable tumor niche and to promote tumor growth, invasiveness and progression.