C
Crystal S. Denlinger
Researcher at Fox Chase Cancer Center
Publications - 164
Citations - 7797
Crystal S. Denlinger is an academic researcher from Fox Chase Cancer Center. The author has contributed to research in topics: Cancer & Survivorship curve. The author has an hindex of 35, co-authored 153 publications receiving 5203 citations.
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Journal ArticleDOI
KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors.
David S. Hong,Marwan Fakih,John H. Strickler,Jayesh Desai,G. Durm,Geoffrey I. Shapiro,Gerald S. Falchook,Timothy J. Price,Adrian G. Sacher,Crystal S. Denlinger,Yung-Jue Bang,Grace K. Dy,John C. Krauss,Yasutoshi Kuboki,James Kuo,Andrew L. Coveler,Keunchil Park,Tae Won Kim,Fabrice Barlesi,Pamela N. Munster,Suresh S. Ramalingam,Timothy F. Burns,Funda Meric-Bernstam,H. Henary,J. Ngang,Gataree Ngarmchamnanrith,J. Kim,Brett E. Houk,Jude Canon,J. Russell Lipford,Gregory Friberg,Piro Lito,Ramaswamy Govindan,Bob T. Li +33 more
TL;DR: Sotorasib showed encouraging anticancer activity in patients with heavily pretreated advanced solid tumors harboring the KRAS p.G12C mutation and responded to pharmacokinetics and objective response according to Response Evaluation Criteria in Solid Tumors (RECIST), version 1.1.
Journal ArticleDOI
Esophageal and Esophagogastric Junction Cancers, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology.
Jaffer A. Ajani,Thomas A. D'Amico,David J. Bentrem,Joseph Chao,Carlos U. Corvera,Prajnan Das,Crystal S. Denlinger,Peter C. Enzinger,Paul T. Fanta,Farhood Farjah,Hans Gerdes,Michael Gibson,Robert E. Glasgow,James A. Hayman,Steven N. Hochwald,Wayne L. Hofstetter,David H. Ilson,Dawn E. Jaroszewski,Kimberly L. Johung,Rajesh N. Keswani,Lawrence Kleinberg,Stephen Leong,Quan P. Ly,Kristina A. Matkowskyj,Michael McNamara,Mary F. Mulcahy,Ravi Kumar Paluri,Haeseong Park,Kyle A. Perry,Jose M. Pimiento,George A. Poultsides,Robert E. Roses,Vivian E. Strong,Georgia L. Wiesner,Christopher G. Willett,Cameron D. Wright,Nicole R. McMillian,Lenora A. Pluchino +37 more
TL;DR: This selection from the NCCN Guidelines for Esophageal and Esophagogastric Junction Cancers focuses on recommendations for the management of locally advanced and metastatic adenocarcinoma of the esophagus and EGJ.
Journal ArticleDOI
Gastric Cancer, Version 3.2016; Clinical Practice Guidelines in Oncology
Jaffer A. Ajani,Thomas A. D'Amico,Khaldoun Almhanna,David J. Bentrem,Joseph Chao,Prajnan Das,Crystal S. Denlinger,Paul T. Fanta,Farhood Farjah,Charles S. Fuchs,Hans Gerdes,Michael K. Gibson,Robert E. Glasgow,James A. Hayman,Steven N. Hochwald,Wayne L. Hofstetter,David H. Ilson,Dawn E. Jaroszewski,Kimberly L. Johung,Rajesh N. Keswani,Lawrence Kleinberg,W. Michael Korn,Stephen Leong,Catherine Linn,A. Craig Lockhart,Quan P. Ly,Mary F. Mulcahy,Mark B. Orringer,Kyle A. Perry,George A. Poultsides,Walter J. Scott,Vivian E. Strong,Mary Kay Washington,Benny Weksler,Christopher G. Willett,Cameron D. Wright,Debra Zelman,Nicole R. McMillian,Hema Sundar +38 more
TL;DR: The recommendations outlined in the NCCN Guidelines for staging, assessment of HER2 overexpression, systemic therapy for locally advanced or metastatic disease, and best supportive care for the prevention and management of symptoms due to advanced disease are discussed.
Journal ArticleDOI
Gastric Cancer, Version 2.2013
Jaffer A. Ajani,David J. Bentrem,Stephen Besh,Thomas A. D'Amico,Prajnan Das,Crystal S. Denlinger,Marwan Fakih,Charles S. Fuchs,Hans Gerdes,Robert E. Glasgow,James A. Hayman,James A. Hayman,Wayne L. Hofstetter,David H. Ilson,Rajesh N. Keswani,Lawrence Kleinberg,Lawrence Kleinberg,W. Michael Korn,A. Craig Lockhart,Kenneth L. Meredith,Mary F. Mulcahy,Mark B. Orringer,Mark B. Orringer,James Posey,Aaron R. Sasson,Walter J. Scott,Vivian E. Strong,Thomas K. Varghese,Graham W. Warren,Mary Kay Washington,Christopher G. Willett,Cameron D. Wright,Nicole R. McMillian,Hema Sundar +33 more
TL;DR: The NCCN Clinical Practice Guidelines in Oncology for Gastric Cancer provide evidence- and consensus-based recommendations for a multidisciplinary approach for the management of patients with gastric cancer.
Journal ArticleDOI
American College of Sports Medicine Roundtable Report on Physical Activity, Sedentary Behavior, and Cancer Prevention and Control.
Alpa V. Patel,Christine M. Friedenreich,Steven C. Moore,Sandra C. Hayes,Julie K. Silver,Kristin L. Campbell,Kerri M. Winters-Stone,Lynn H. Gerber,Stephanie M. George,Janet E. Fulton,Crystal S. Denlinger,G. Stephen Morris,Trisha F. Hue,Kathryn H. Schmitz,Charles E. Matthews +14 more
TL;DR: There is consistent, compelling evidence that physical activity plays a role in preventing many types of cancer and for improving longevity among cancer survivors, although the evidence related to higher risk of melanoma demonstrates the importance of sun safe practices while being physically active.