Cui Yang

Bio: Cui Yang is an academic researcher from Shenzhen University. The author has contributed to research in topics: Transducer & Phased array ultrasonics. The author has an hindex of 2, co-authored 2 publications receiving 12 citations.

Two-dimensional annular phased array ultrasonic transducer structure

Abstract: The invention discloses a two-dimensional annular phased array ultrasonic transducer structure for three-dimensional ultrasonic imaging. The transducer structurally comprises more than one array element ring which is annularly distributed in a concentric circle way, and each array element ring comprises more than two array elements, and the area of each array element is the same. According to the two-dimensional annular phased array ultrasonic transducer structure, the defect of signal to noise ratio caused by high technical process difficulty and small array element size of a two-dimensional area array transducer can be overcome, and the limit that a one-dimensional array and a phased array are in geometric focusing fixing, and a wave beam cannot be effectively narrowed can be overcome, so that the lateral resolution can be comprehensively improved, the signal to noise ratio can be effectively increased, and real-time three-dimensional ultrasonic imaging can be realized by electronic phased scanning.

New focused ultrasound transducer for fat cell disruption

Abstract: Being an emerging body-shaping technology of fat cell disruption, high-intensity focused ultrasound has been investigated intensively in recent years for its favorable natures such as painlessness, safety and noninvasion. One of the major problems for the technology, however, is the overheating of transducers. In this study, we modified the transducer design in order to solve the overheating problem. We simulated the performance of the modified design by finite element analysis and fabricated the newly designed transducer. By measuring the actual performance data, we proved that the new design can effectively reduce temperature rise while keeping the acoustic intensity field unaffected.

Review on triggered liposomal drug delivery with a focus on ultrasound.

Abstract: Chemotherapy is widely used for cancer treatment; however, it causes unwanted side effects in patients. To avoid these adverse effects, nanocarriers have been developed, which can be loaded with the chemotherapeutic agents, directed to the cancer site and, once there, are exposed to stimuli that will trigger the drug release. Liposomes can be chemically modified to increase their circulation time, their stability, and their sensitivity to specific stimulus. Additionally, ligands can be conjugated to their surface, allowing for their specific binding to receptors overexpressed on the surface of cancer cells and the subsequent internalization via endocytosis. Using a triggering mechanism, including temperature, ultrasound, enzymes or a change in pH, the release of the drug is controlled and induced inside the cells, hence avoiding drug release in systemic circulation, which in turn reduces the undesired side effects of conventional chemotherapy. Ultrasound has been widely studied as a drug release trigger from liposomes, due to its well-known physics and previous uses in medicine. This review focuses on liposome-based drug delivery systems, using different trigger mechanisms, with a focus on ultrasound. The physical mechanisms of ultrasound release are also investigated and the results of in vitro and in vivo studies are summarized.

Transcranial Doppler plane annular phased array probe

Abstract: The invention provides a transcranial Doppler plane annular phased array probe, which comprises a piezoelectric vibrator, a metal shielding casing, an electronic tuning circuit, a coaxial cable, a case, a back lining, a matching layer and an acoustic lens, wherein the piezoelectric vibrator comprises more than one array element ring in annular distribution to form concentric circles, each array element ring adopts independent lead wire control, the areas of all array elements are identical, in addition, the path differences of all array elements are identical, each independent array element is excited by adopting specific time delay, and the dynamic focusing in the spreading direction of ultrasonic beams can be achieved. The plane annular phased array is utilized, each array element is respectively subjected to time delay during the emitting or receiving, and the emitting focusing or the receiving focusing is realized, so focal points can be continuously adjusted, the ultrasonic beams can be effectively and controllably narrowed, the depth of field is long, the transcranial Doppler plane annular phased array probe has the advantages of variable aperture, variable focal point, variable trace and the like, the lateral resolution ratio of a system can be comprehensively improved, and the signal to noise ratio is effectively improved.

Liposomal drug release using ultrasound and modeling release dynamics for model predictive controller design

Abstract: A Master of Science thesis in Electrical Engineering by Hesham Gamal Moussa entitled, "Liposomal drug release using ultrasound and modeling release dynamics for model predictive controller design," submitted in June 2015. Thesis advisors are Dr. Nasser Qaddoumi and Dr. Ghaleb Husseini. Soft and hard copy available.

Jet angle controllable ultrasonic droplet jetting additive manufacturing device and method

Abstract: The invention relates to jet angle controllable ultrasonic droplet jetting additive manufacturing device and method, belonging to the field of additive manufacturing. The device is characterized in that a base is installed at the bottom; a jet tank is installed on the base; a focused ultrasonic transducer is installed in the jet tank; a base plate is fixed below wafer bearing platforms and above the jet tank; the wafer bearing platforms are installed on a Z-direction workbench; the Z-direction workbench is installed on the base; the jet tank is communicated with a liquid storage tank; a high-precision injection pump is connected with a feeding head; through focused ultrasound, liquid overcomes the surface tension and jets droplets from the liquid level; the power of four focused ultrasonic vibrators of the focused ultrasonic transducer is controlled by a computer and the focused ultrasonic vibrators interact and then change the jet angles of the droplets to jet the droplets to different positions on the base plate; a Z-axis motion platform cooperates with different jet angles to complete printing of different position points on the base plate. The device and the method have the effects of improving the printing precision and ensuring the physical and chemical properties and other properties of formed parts without needing print heads, thus avoiding pollution and cleaning difficulty of liquid materials.

Sensor structure with periodic band gap structure

Abstract: The invention discloses a sensor structure with a periodic band gap structure. The sensor structure comprises a plurality of one-dimensional phononic crystal sector structures arranged at the same center, and a plurality of piezoelectric sensors correspondingly arranged inside the one-dimensional phononic crystal sector structures one by one, wherein an air anti-interference zone is arranged between adjacent one-dimensional phononic crystal sector structures at the same time. The invention has the advantages that the sensor structure is designed by using a periodic structure and made of acoustic super material forming an optical band gap structure, and the sensing signal is enhanced by using the local resonance effect on the special frequency band of the signal, thereby achieving the purpose of improving the sensitivity of the sensor, and making the designed sensor structure have special physical properties.