C
Cyrus Cooper
Researcher at Southampton General Hospital
Publications - 1961
Citations - 248928
Cyrus Cooper is an academic researcher from Southampton General Hospital. The author has contributed to research in topics: Population & Osteoporosis. The author has an hindex of 204, co-authored 1869 publications receiving 206782 citations. Previous affiliations of Cyrus Cooper include University of Oxford & University of York.
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Journal ArticleDOI
Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals
Tuomas O. Kilpeläinen,M. den Hoed,Ken K. Ong,Anders Grøntved,Soren Brage,Karen A. Jameson,Cyrus Cooper,Khaw K-T.,Khaw K-T.,Ulf Ekelund,Ulf Ekelund,Nicholas J. Wareham,Loos Rjf. +12 more
TL;DR: Examining associations of 12 established BMI variants in or near the NEGR1, SEC16B, TMEM18, ETV5, GNPDA2, BDNF, MTCH2, BCDIN3D, SH2B1, FTO, MC4R, and KCTD15 genes and their additive score with birth weight found some evidence of an association was found for theMTCH2 and FTO loci.
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Influence of hormonal and reproductive factors on the risk of vertebral deformity in European women
TL;DR: Oestrogen status is an important determinant of vertebral deformity across Europe and ever use of the oral contraceptive pill was associated with a 25% reduction in risk of deformity though the effect may be a result of the higher-dosage oestrogen pills used in the past.
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Falls Predict Fractures Independently of FRAX Probability: A Meta-Analysis of the Osteoporotic Fractures in Men (MrOS) Study
Nicholas C. Harvey,Anders Odén,Eric S. Orwoll,Jodi Lapidus,Timothy Kwok,Magnus Karlsson,Björn E. Rosengren,Östen Ljunggren,Cyrus Cooper,Eugene V. McCloskey,John A. Kanis,Claes Ohlsson,Dan Mellström,Helena Johansson +13 more
TL;DR: It is confirmed that past falls predicted incident fracture independently of FRAX probability, confirming the potential value of falls history in fracture risk assessment.
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Lean Mass, Muscle Strength and Gene Expression in Community Dwelling Older Men: Findings from the Hertfordshire Sarcopenia Study (HSS)
Harnish P. Patel,Nasser Al-Shanti,Lucy Davies,Sheila J. Barton,Miranda D. Grounds,Ross L. Tellam,Claire E. Stewart,Cyrus Cooper,Avan Aihie Sayer +8 more
TL;DR: Lower expression of VDR and IFNG is associated with higher lean mass, and lower expression of IL-6, TNF, IL1R1 and myostatin is associatedwith higher grip strength, consistent with a role of proinflammatory factors in mediating lower muscle strength in community-dwelling older men.
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Disease-specific perception of fracture risk and incident fracture rates: GLOW cohort study
Celia L Gregson,Celia L Gregson,Elaine M. Dennison,Juliet E. Compston,Silvano Adami,Jonathan D. Adachi,Frederick A. Anderson,Steven Boonen,Roland Chapurlat,Adolfo Diez-Perez,Susan L. Greenspan,Frederick H. Hooven,Andrea Z. LaCroix,Jeri W. Nieves,J C Netelenbos,Johannes Pfeilschifter,Maurizio Rossini,C. Roux,Kenneth G. Saag,S. Silverman,Ethel S. Siris,Nelson B. Watts,Allison Wyman,Cyrus Cooper,Cyrus Cooper +24 more
TL;DR: Postmenopausal women with morbidities tend to under-appreciate their risk, including in the context of neurological diseases, where fracture rates were highest in this cohort.