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D. Sen

Bio: D. Sen is an academic researcher from University of Calcutta. The author has contributed to research in topics: Amino acid synthesis & Photo-reactive amino acid analog. The author has an hindex of 2, co-authored 3 publications receiving 10 citations.

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Journal ArticleDOI
TL;DR: Investigation of the mechanism of the inhibitory action of the new N-pyrimidyl compounds in S. faecalis revealed that they acted primarily as folic acid antagonists in a manner consistent with an assumption that they interfere with the enzymatic conversion of folic Acid to 5 N-forrnyl tetrahydrofolic acid.

7 citations

Journal ArticleDOI
TL;DR: In this article, the synthesis of 2(4)-imidazol-1-yl-4(2)-cycloalkylaminopyrimidines are reported, which demonstrated a marked antiaggregating activity superior to dipyridamole, ASA, ticlopidine and similar to that of indobufen.

6 citations

Journal ArticleDOI
29 Dec 1962-Nature
TL;DR: Tanaka et al. as mentioned in this paper showed that 5-arylazo pyrimidines having different groups (for example, hydroxyl, methyl or amino) at the 2, 4 and 6 positions are strong folio acid antagonists and that some of these possess marked anti-neoplastic properties.
Abstract: IT was shown by Tanaka et al.1,2 that 5-arylazo pyrimidines having different groups (for example, hydroxyl, methyl or amino) at the 2, 4 and 6 positions are strong folio acid antagonists and that some of these possess marked anti-neoplastic properties. They also found that the nature of substituents in the benzene ring of the phenylazo radical was the determining factor for this activity.

3 citations

Journal ArticleDOI
TL;DR: In this paper, the authors introduce the concept of photodecomposition of unsaturated compounds and demonstrate the use of photoderiversion in the context of trans-isomerization and dimerization.
Abstract: CONTENTS I. Introduction 678 II. Sensitized photodecomposition 679 III. Sensitized intramolecular rearrangements 682 IV. Sensitized cis–trans-isomerization 682 V. Sensitized dimerization and polymerization of unsaturated compounds 684 VI. Oxidation–reduction reactions 685

2 citations