D
Da-Wei Huang
Researcher at National Institutes of Health
Publications - 189
Citations - 56560
Da-Wei Huang is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & Fig wasp. The author has an hindex of 38, co-authored 172 publications receiving 48460 citations. Previous affiliations of Da-Wei Huang include Montreal General Hospital & Beijing Institute of Genomics.
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Journal ArticleDOI
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.
TL;DR: By following this protocol, investigators are able to gain an in-depth understanding of the biological themes in lists of genes that are enriched in genome-scale studies.
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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
TL;DR: The survey will help tool designers/developers and experienced end users understand the underlying algorithms and pertinent details of particular tool categories/tools, enabling them to make the best choices for their particular research interests.
Journal ArticleDOI
The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists
Da-Wei Huang,Brad T. Sherman,Qina Tan,Jack R. Collins,W. Gregory Alvord,Jean Roayaei,Robert S Stephens,Michael Baseler,H. Clifford Lane,Richard A. Lempicki +9 more
TL;DR: The DAVID Gene Functional Classification Tool uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules, for efficient interpretation of gene lists in a network context.
Journal ArticleDOI
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists
Da-Wei Huang,Brad T. Sherman,Qina Tan,Joseph Kir,David R. Liu,David Bryant,Yongjian Guo,Robert M. Stephens,Michael Baseler,H. Clifford Lane,Richard A. Lempicki +10 more
TL;DR: The expanded DAVID Knowledgebase now integrates almost all major and well-known public bioinformatics resources centralized by the DAVID Gene Concept, a single-linkage method to agglomerate tens of millions of diverse gene/protein identifiers and annotation terms from a variety of public bio informatics databases.
Journal ArticleDOI
Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma
Roland Schmitz,George E. Wright,Da-Wei Huang,Calvin A. Johnson,James D. Phelan,James Q. Wang,Sandrine Roulland,Monica Kasbekar,Ryan M. Young,Arthur L. Shaffer,Daniel J. Hodson,Wenming Xiao,Xin Yu,Yandan Yang,Hong Zhao,Weihong Xu,Xuelu Liu,Bin Zhou,Wei Du,Wing C. Chan,Elaine S. Jaffe,Randy D. Gascoyne,Joseph M. Connors,Elias Campo,Armando López-Guillermo,Andreas Rosenwald,German Ott,Jan Delabie,Lisa M. Rimsza,Kevin Tay Kuang Wei,Andrew D. Zelenetz,Andrew D. Zelenetz,John P. Leonard,John P. Leonard,Nancy L. Bartlett,Nancy L. Bartlett,Bao Tran,Jyoti Shetty,Yongmei Zhao,Dan R. Soppet,Stefania Pittaluga,Wyndham H. Wilson,Louis M. Staudt +42 more
TL;DR: Analysis of genetic pathways suggested that MCD and BN2 DLBCLs rely on “chronic active” B‐cell receptor signaling that is amenable to therapeutic inhibition, and an algorithm was developed and implemented to discover genetic subtypes based on the co‐occurrence of genetic alterations.