D
Dae Hyun Roh
Researcher at Kyung Hee University
Publications - 80
Citations - 2758
Dae Hyun Roh is an academic researcher from Kyung Hee University. The author has contributed to research in topics: Nociception & Neuropathic pain. The author has an hindex of 30, co-authored 77 publications receiving 2494 citations. Previous affiliations of Dae Hyun Roh include Seoul National University & Chonnam National University.
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Journal ArticleDOI
Wound healing effect of silk fibroin/alginate-blended sponge in full thickness skin defect of rat
Dae Hyun Roh,Seuk-Yun Kang,Jeom-Yong Kim,Young Bae Kwon,Hae Young Kweon,Kwang-Gill Lee,Young Hwan Park,Rong Min Baek,Chan Yeong Heo,Joon Choe,Jang Hern Lee +10 more
TL;DR: The results demonstrate that the wound healing effect of SF/AA is the best among other treatments including SF and AA, and this synergic effect is mediated by re-epithelialization via rapid proliferation of epithelial cell.
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Intrathecal injection of the ς1 receptor antagonist BD1047 blocks both mechanical allodynia and increases in spinal NR1 expression during the induction phase of rodent neuropathic pain
Dae Hyun Roh,Hyun-Woo Kim,Seo Yeon Yoon,Hyoung Sig Seo,Young Bae Kwon,Kee-Won Kim,Ho Jae Han,Alvin J. Beitz,Heung Sik Na,Jang Hern Lee +9 more
TL;DR: Results demonstrate that spinal Sig-1Rs play a critical role in both the induction of mechanical allodynia and the activation of spinal N-methyl-d-aspartate receptors in CCI rats and suggest a potential therapeutic role for the use of Sig- 1R antagonists in the clinical management of neuropathic pain.
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Activation of the spinal sigma‐1 receptor enhances NMDA‐induced pain via PKC‐ and PKA‐dependent phosphorylation of the NR1 subunit in mice
Hyun-Woo Kim,Dae Hyun Roh,Seo Yeon Yoon,Hyoung Sig Seo,Young Bae Kwon,Ho Jae Han,Kee-Won Kim,Alvin J. Beitz,Jang Hern Lee +8 more
TL;DR: It is demonstrated that the spinal sigma‐1 receptor (Sig‐1 R) plays an important role in pain transmission, although the exact mechanism is still unclear and there are no studies addressing whether Sig-1 R activation directly affects NMDA receptor sensitivity.
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Acupoint Stimulation Using Bee Venom Attenuates Formalin-Induced Pain Behavior and Spinal Cord Fos Expression in Rats
Hyun-Woo Kim,Young Bae Kwon,Tae Won Ham,Dae Hyun Roh,Seo Yeon Yoon,Hyejung Lee,Ho Jae Han,Il Suk Yang,Alvin J. Beitz,Jang Hern Lee +9 more
TL;DR: Findings indicate that BV pretreatment into the Zusanli acupoint has an antinociceptive effect on formalin-induced pain behavior.
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Intrathecal treatment with σ1 receptor antagonists reduces formalin-induced phosphorylation of NMDA receptor subunit 1 and the second phase of formalin test in mice
Hyun-Woo Kim,Young Bae Kwon,Dae Hyun Roh,Seo Yeon Yoon,Ho Jae Han,Kee-Won Kim,Alvin J. Beitz,Jang Hern Lee +7 more
TL;DR: It is suggested that selective blockage of spinal σ1 receptors can reduce pain behaviors, spinal cord Fos expression and pNR1 (Ser896 and Ser897) expression associated with the second phase of the formalin test.