Author
Dale Dominey-Howes
Other affiliations: University of Manitoba, Macquarie University, University of New South Wales ...read more
Bio: Dale Dominey-Howes is an academic researcher from University of Sydney. The author has contributed to research in topics: Vulnerability & Vulnerability assessment. The author has an hindex of 40, co-authored 141 publications receiving 4925 citations. Previous affiliations of Dale Dominey-Howes include University of Manitoba & Macquarie University.
Papers published on a yearly basis
Papers
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TL;DR: It is proposed that in addition to current measures and increased research into new antimicrobials and diagnostics, a comprehensive education program will be required to change the public paradigm of antimicrobial usage from that of a first line treatment to that of an last resort when all other therapeutic options have failed.
Abstract: The antimicrobial resistance (AMR) crisis is the increasing global incidence of infectious diseases affecting the human population, which are untreatable with any known antimicrobial agent. This crisis will have a devastating cost on human society as both debilitating and lethal diseases increase in frequency and scope. Three major factors determine this crisis: (1) the increasing frequency of AMR phenotypes among microbes is an evolutionary response to the widespread use of antimicrobials; (2) the large and globally connected human population allows pathogens in any environment access to all of humanity; and (3) the extensive and often unnecessary use of antimicrobials by humanity provides the strong selective pressure that is driving the evolutionary response in the microbial world. Of these factors, the size of the human population is least amenable to rapid change. In contrast, the remaining two factors may be affected, so offering a means of managing the crisis: the rate at which AMR, as well as virulence factors evolve in microbial world may be slowed by reducing the applied selective pressure. This may be accomplished by radically reducing the global use of current and prospective antimicrobials. Current management measures to legislate the use of antimicrobials and to educate the healthcare world in the issues, while useful, have not comprehensively addressed the problem of achieving an overall reduction in the human use of antimicrobials. We propose that in addition to current measures and increased research into new antimicrobials and diagnostics, a comprehensive education program will be required to change the public paradigm of antimicrobial usage from that of a first line treatment to that of a last resort when all other therapeutic options have failed.
603 citations
TL;DR: In this article, the authors review progress with the development of these criteria and identify opportunities for refinements and for extending their application to new settings, with the emphasis on promoting the use of multiple proxies, selected to best match the context of the site or region of interest.
261 citations
TL;DR: In this article, the authors identify the need for a specific framework identifying how indigenous and western knowledge may be combined to mitigate against the intrinsic effects of environmental processes and therefore reduce the vulnerability of rural indigenous communities in small island developing states (SIDS) to environmental hazards.
252 citations
TL;DR: In this paper, the authors reviewed some of the proxies used to identify palaeotsunamis, and provided a revised toolkit for the analysis of tsunami data using anisotropy of magnetic susceptibility (AMS).
188 citations
TL;DR: The Destination Sustainability Framework (DSF) as discussed by the authors is designed to assess destination vulnerability and resilience, and support successful resilience-building initiatives Holistic in nature, the DSF comprises: (1) the shock(s) or stressor(s); (2) the interconnected dimensions of vulnerability, exposure, sensitivity, and system adaptiveness; (3) the dynamic feedback loops that express the multiple outcomes of actions taken (or not); (4) the contextualised root causes that shape destinations and their characteristics; and (5) the various spatial scales.
Abstract: Tourism is a key driver of global socio-economic progress However, its sustainability is at risk from multiple shocks and hazards that threaten livelihoods Surprisingly little is known about the complex drivers of destination vulnerability, leading to the creation and application of ineffective resilience-building solutions The paper presents the Destination Sustainability Framework (DSF) designed to assess destination vulnerability and resilience, and support successful resilience-building initiatives Holistic in nature, the DSF comprises: (1) the shock(s) or stressor(s); (2) the interconnected dimensions of vulnerability – exposure, sensitivity, and system adaptiveness; (3) the dynamic feedback loops that express the multiple outcomes of actions taken (or not); (4) the contextualised root causes that shape destinations and their characteristics; (5) the various spatial scales; and (6) multiple timeframes within which social-ecological change occurs This innovative framework is significant because i
172 citations
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TL;DR: Decades after the first patients were treated with antibiotics, bacterial infections have again become a threat because of the rapid emergence of resistant bacteria-a crisis attributed to abuse of these medications and a lack of new drug development.
Abstract: Decades after the first patients were treated with antibiotics, bacterial infections have again become a threat because of the rapid emergence of resistant bacteria-a crisis attributed to abuse of these medications and a lack of new drug development.
3,147 citations
2,204 citations