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Daniel Amaro Sousa
Researcher at Universidade Católica de Brasília
Publications - 7
Citations - 440
Daniel Amaro Sousa is an academic researcher from Universidade Católica de Brasília. The author has contributed to research in topics: Antimicrobial peptides & Proteome. The author has an hindex of 6, co-authored 7 publications receiving 388 citations. Previous affiliations of Daniel Amaro Sousa include University of Brasília.
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Journal ArticleDOI
Antimicrobial peptides from marine invertebrates as a new frontier for microbial infection control
Anselmo J. Otero-González,Beatriz Simas Magalhães,Monica Garcia-Villarino,Carlos López-Abarrategui,Daniel Amaro Sousa,Simoni Campos Dias,Octavio L. Franco +6 more
TL;DR: A promising novel use of antimicrobial peptides as effective drugs in human and veterinary medicine could be based on their unusual properties and synergic counterparts as immune response humoral effectors, in addition to their direct microbicidal activity.
Journal ArticleDOI
The use of versatile plant antimicrobial peptides in agribusiness and human health.
Elizabete de Souza Cândido,Marlon H. Cardoso,Daniel Amaro Sousa,Juliane F.C. Viana,Nelson G. Oliveira-Júnior,Vívian de Jesus Miranda,Octavio L. Franco,Octavio L. Franco +7 more
TL;DR: This review will focus on the relevance of the structural-function relations of AMPs derived from plants and their proper use in applications for human health and agribusiness.
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Identification and Structural Characterization of Novel Cyclotide with Activity against an Insect Pest of Sugar Cane
Michelle F. S. Pinto,Isabel C. M. Fensterseifer,Ludovico Migliolo,Daniel Amaro Sousa,Guy de Capdville,Jorge W. Arboleda-Valencia,Jorge W. Arboleda-Valencia,Michelle L. Colgrave,David J. Craik,Beatriz Simas Magalhães,Simoni Campos Dias,Octavio L. Franco +11 more
TL;DR: Parigidin-br1 showed potent insecticidal activity against neonate larvae of Lepidoptera (Diatraea saccharalis), causing 60% mortality at a concentration of 1 μm but had no detectable antibacterial effects.
Journal ArticleDOI
Deciphering the magainin-resistance process of Escherichia coli strains in light of the cytosolic proteome
Simone Maria-Neto,Elizabete de Souza Cândido,Diana Ribas Rodrigues,Daniel Amaro Sousa,Daniel Amaro Sousa,Ezequiel Marcelino da Silva,Lidia Maria Pepe de Moraes,Anselmo J. Otero-González,Beatriz Simas Magalhães,Simoni Campos Dias,Octavio L. Franco,Octavio L. Franco,Octavio L. Franco +12 more
TL;DR: Data reported here show that resistance to cationic antimicrobial peptides possesses a greater molecular complexity than previously supposed, resulting in cell commitment to several metabolic pathways.
Journal ArticleDOI
Influence of Cysteine and Tryptophan Substitution on DNA-Binding Activity on Maize α-Hairpinin Antimicrobial Peptide
Daniel Amaro Sousa,Daniel Amaro Sousa,William F. Porto,Maria Z Silva,Tatiane R da Silva,Octavio L. Franco,Octavio L. Franco,Octavio L. Franco +7 more
TL;DR: Molecular modelling showed that the lack of cysteines resulted in structure destabilization and lack of tryptophan resulted in a less flexible peptide, with less solvent assessable surface area, both characteristics that could contribute to absence of activity.