D
Daniel Branton
Researcher at Harvard University
Publications - 221
Citations - 34325
Daniel Branton is an academic researcher from Harvard University. The author has contributed to research in topics: Spectrin & Nanopore. The author has an hindex of 86, co-authored 221 publications receiving 33074 citations. Previous affiliations of Daniel Branton include University of California & Rowland Institute for Science.
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Journal ArticleDOI
Characterization of individual polynucleotide molecules using a membrane channel
TL;DR: It is shown that an electric field can drive single-stranded RNA and DNA molecules through a 2.6-nm diameter ion channel in a lipid bilayer membrane, which could in principle provide direct, high-speed detection of the sequence of bases in single molecules of DNA or RNA.
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The Potential and Challenges of Nanopore Sequencing
Daniel Branton,David W. Deamer,Andre Marziali,Hagan Bayley,Steven A. Benner,Thomas Z. Butler,Massimiliano Di Ventra,Slaven Garaj,Andrew Hibbs,Xiaohua Huang,Stevan B Jovanovich,Predrag S Krstic,Stuart Lindsay,Xinsheng Sean Ling,Carlos H. Mastrangelo,Amit Meller,John S. Oliver,Yuriy V. Pershin,J. Michael Ramsey,Robert Riehn,Gautam V. Soni,Vincent Tabard-Cossa,Meni Wanunu,Matthew Wiggin,Jeffery A. Schloss +24 more
TL;DR: A nanopore-based device provides single-molecule detection and analytical capabilities that are achieved by electrophoretically driving molecules in solution through a nano-scale pore, a unique analytical capability that makes inexpensive, rapid DNA sequencing a possibility.
Journal ArticleDOI
Ion-beam sculpting at nanometre length scales
Jiali Li,Derek Stein,Ciaran J. McMullan,Daniel Branton,Michael J. Aziz,Jene Andrew Golovchenko +5 more
TL;DR: It is shown that ion-beam sculpting can be used to fashion an analogous solid-state device: a robust electronic detector consisting of a single nanopore in a Si3N4 membrane, capable of registering single DNA molecules in aqueous solution.
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Graphene as a subnanometre trans-electrode membrane
Slaven Garaj,William A. Hubbard,Alfonso Reina,Jing Kong,Daniel Branton,Jene Andrew Golovchenko +5 more
TL;DR: It is shown that when immersed in an ionic solution, a layer of graphene becomes a new electrochemical structure that is called a trans-electrode, which is an ideal substrate for very high resolution, high throughput nanopore-based single-molecule detectors.
Journal ArticleDOI
Freeze-etching nomenclature.
Daniel Branton,S. Bullivant,Norton B. Gilula,Morris J. Karnovsky,H. Moor,K. Mühlethaler,D. H. Northcote,Lester Packer,Birgit Satir,Peter Satir,Volker Speth,L. A. Staehlin,Russell L. Steere,Ronald S. Weinstein +13 more
TL;DR: Results indicate that the host-versus-graft reaction alone can enihance murine cvtomtiegalovirus in a chronicallY injected host atid maY help explain the high incidence of cvvtomegalov virus infection seen after renal and other allograft transplantation.