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Daniel M. Jones

Researcher at University of Oxford

Publications -  12
Citations -  1505

Daniel M. Jones is an academic researcher from University of Oxford. The author has contributed to research in topics: Medicine & Furin. The author has an hindex of 6, co-authored 9 publications receiving 1147 citations. Previous affiliations of Daniel M. Jones include Wellcome Trust Centre for Human Genetics.

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Reproducibility in density functional theory calculations of solids

Kurt Lejaeghere, +79 more
- 25 Mar 2016 - 
TL;DR: A procedure to assess the precision of DFT methods was devised and used to demonstrate reproducibility among many of the most widely used DFT codes, demonstrating that the precisionof DFT implementations can be determined, even in the absence of one absolute reference code.
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Toremifene interacts with and destabilizes the Ebola virus glycoprotein.

TL;DR: The results suggest that inhibitor binding destabilizes GP and triggers premature release of GP2, thereby preventing fusion between the viral and endosome membranes, which reveals the mechanism of inhibition and may guide the development of more powerful anti-EBOV drugs.
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Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material

TL;DR: It is confirmed that astrocytes trap and internalize HIV-1 particles for subsequent release but finding no evidence that these particles infect the cell, which has implications for HIV- 1 infection of the CNS, viral reservoir formation, and antiretroviral therapy.
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The β-Lactamase Assay: Harnessing a FRET Biosensor to Analyse Viral Fusion Mechanisms

TL;DR: A review of the methodologies used to render viruses compatible with BlaM-based analyses draws attention to the disparity of these methodologies and examines the advantages and disadvantages of each approach.
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Dynamin-2 Stabilizes the HIV-1 Fusion Pore with a Low Oligomeric State

TL;DR: The data suggest that dynamin-2, as a tetramer, might help to establish hemi-fusion and stabilizes the pore during HIV-1 fusion.