Daniela Melchiorri

TL;DR: Melatonin is remarkably potent in protecting against free radical damage induced by a variety of means, and DNA damage resulting from either the exposure of animals to the chemical carcinogen safrole or to ionizing radiation is markedly reduced when melatonin is co‐administered.

TL;DR: A series of observations suggest a potential application of mGlu5 receptor antagonists in chronic neurodegenerative disorders, such as amyotrophic lateral sclerosis and Alzheimer disease.

TL;DR: It is suggested that melatonin confers marked protection against paraquat-induced oxidative toxicity in both the lung and liver.

TL;DR: In this model of liver ischemia-reperfusion injury, exogenously administered melatonin effectively protected against oxidative damage, the hepatic parameters which illustrated this protection were reduced lipid peroxidation products, lowered PMN infiltration, increased GSH and reduced G SSG levels, and elevated GSSG-Rd activity all of which were observed in melatonin-treated rats.

TL;DR: Melatonin protection against in vitro kainic acid‐induced oxidative damage in homogenates from different rat brain regions is shown and is likely due, at least in part, to its newly discovered, free radical scavenging ability.