Daniela Walterová

TL;DR: This review critically surveys the literature published mainly within this millennium on the new and emerging applications of silybin (pure, chemically defined substance) and silymarin (flavonoid complex from Silybum marianum - milk thistle seeds).

TL;DR: This review strives to summarize the findings of studies performed to date, regarding the photoprotective effects of plant phenolics on the skin damage induced by UV radiation.

TL;DR: This article aims to review critically literature published mainly within this millennium on the new and emerging applications of silymarin, the polyphenolic fraction from the seeds of Silybum marianum and its main component silybin, to suggest new mechanisms of its action.

TL;DR: The endogenous and exogenous mechanisms of skin photoprotection are discussed, where the UV light is absorbed by endogenous sensitizers that are excited and their further reactions lead to formation of reactive oxygen species (ROS).

TL;DR: It is established the importance of the 3-OH and 20-OH groups as H donors, in the presence of the 2,3 double bond and the catechol moiety in the E-ring, respectively, and secondary mechanisms could become more important as the active sites for H atom transfer (HAT) mechanism are much less effective (high BDEs).