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Danielle Belgrave
Researcher at Microsoft
Publications - 63
Citations - 3655
Danielle Belgrave is an academic researcher from Microsoft. The author has contributed to research in topics: Population & Wheeze. The author has an hindex of 28, co-authored 61 publications receiving 2699 citations. Previous affiliations of Danielle Belgrave include Manchester Academic Health Science Centre & University of Manchester.
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Journal ArticleDOI
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations
Klaus Bønnelykke,Patrick M. A. Sleiman,Kasper Nielsen,Eskil Kreiner-Møller,Josep M. Mercader,Danielle Belgrave,Herman T. den Dekker,Anders Husby,Astrid Sevelsted,Grissel Faura-Tellez,Li Juel Mortensen,Lavinia Paternoster,Richard Flaaten,Anne Mølgaard,David E. Smart,Philip Francis Thomsen,Morten Arendt Rasmussen,Sílvia Bonàs-Guarch,Claus Holst,Ellen A. Nohr,Rachita Yadav,Michael E. March,Thomas Blicher,Peter M. Lackie,Vincent W. V. Jaddoe,Angela Simpson,John W. Holloway,Liesbeth Duijts,Adnan Custovic,Donna E. Davies,David Torrents,Ramneek Gupta,Mads V. Hollegaard,David M. Hougaard,Hakon Hakonarson,Hans Bisgaard +35 more
TL;DR: The results demonstrate the strength of applying specific phenotyping in the search for asthma susceptibility genes, and obtain strong evidence for a new susceptibility gene, CDHR3 (encoding cadherin-related family member 3), which is highly expressed in airway epithelium.
Journal ArticleDOI
Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations.
Helen A. Brough,Angela Simpson,Kerry Makinson,Jenny Hankinson,Sara J. Brown,Abdel Douiri,Danielle Belgrave,Danielle Belgrave,Martin Penagos,Alick Stephens,W.H. Irwin McLean,Victor Turcanu,Nicolaos Nicolaou,Adnan Custovic,Gideon Lack +14 more
TL;DR: Early-life environmental peanut exposure is associated with an increased risk of peanut sensitization and allergy in children who carry an FLG mutation, and data support the hypothesis that peanut allergy develops through transcutaneous sensitization in children with an impaired skin barrier.
Journal ArticleDOI
Developmental Profiles of Eczema, Wheeze, and Rhinitis: Two Population-Based Birth Cohort Studies
Danielle Belgrave,Raquel Granell,Angela Simpson,John Guiver,Christopher M. Bishop,Iain Buchan,A. John Henderson,Adnan Custovic +7 more
TL;DR: Using data from two population-based birth cohorts, Danielle Belgrave and colleagues examine the evidence for atopic march in developmental profiles for allergic disorders.
Journal ArticleDOI
Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies
Danielle Belgrave,Raquel Granell,Steve Turner,John A. Curtin,Iain Buchan,Peter N. Le Souëf,Angela Simpson,A. John Henderson,Adnan Custovic +8 more
TL;DR: Reduction of childhood smoke exposure and minimisation of the risk of early-life sensitisation and wheezing exacerbations might reduce therisk of diminished lung function in early adulthood.