Danijela Krstić

TL;DR: An overview of toxicology and pharmacology of reversible and irreversible acetylcholinesterase inactivating compounds is presented, with emphasis on oxime reactivators of the inhibited enzyme activity administering as causal drugs after the poisoning.

TL;DR: In this paper, the effects of inhibiting Na+/K+-ATPase alpha 1 in human GBM cells with respect to cell proliferation; morphology; impact on intracellular Na+, Ca2+, and adenosine triphosphate; and changes in the actin cytoskeleton were investigated.

TL;DR: Although after 15-min diazinon irradiation formed products do not affect purified commercial enzymes activities, inhibitory effect of irradiated solutions on cell enzymes increased as a function of time exposure to UV light and resulted in significant reduction of AChE and Na(+)/K(+)-ATPase at the end of irradiation period.

TL;DR: Sulphur-containing amino acids represent a powerful part of cell antioxidant system and may offer a chelating site for heavy metals as antioxidant agents against free radicals, providing beneficial effects in eliminating toxic metals.

TL;DR: Although a wide range of biological activities of polyoxometalates was reported, they are not close to clinical trials and the final application in the treatment of diabetes, infectious and malignant diseases, and biomedical studies should be performed on solution-stable compounds under physiological conditions and concentrations employed.