D
Danilo Grünig Humberto da Silva
Researcher at Sao Paulo State University
Publications - 31
Citations - 428
Danilo Grünig Humberto da Silva is an academic researcher from Sao Paulo State University. The author has contributed to research in topics: Oxidative stress & Sickle cell anemia. The author has an hindex of 10, co-authored 26 publications receiving 317 citations. Previous affiliations of Danilo Grünig Humberto da Silva include Federal University of Mato Grosso do Sul.
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Journal ArticleDOI
Oxidative stress in sickle cell disease: an overview of erythrocyte redox metabolism and current antioxidant therapeutic strategies.
Danilo Grünig Humberto da Silva,Edis Belini Junior,Eduardo Alves de Almeida,Claudia Regina Bonini-Domingos +3 more
TL;DR: Sickle cell disease is intimately linked to a pathophysiologic condition of multiple sources of pro-oxidant processes with consequent chronic and systemic oxidative stress, and newer therapeutic agents that can target oxidative stress may constitute a valuable means for preventing or delaying the development of organ complications.
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Hemoglobin D-Punjab: origin, distribution and laboratory diagnosis
Lidiane de Souza Torres,Jéssika Viviani Okumura,Danilo Grünig Humberto da Silva,Claudia Regina Bonini-Domingos +3 more
TL;DR: Information about the origin, geographic distribution, characterization and occurrence of hemoglobin D-Punjab haplotypes is summarized to try to improve knowledge of this variant.
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Effect of melatonin intake on oxidative stress biomarkers in male reproductive organs of rats under experimental diabetes
Marina Guimarães Gobbo,Marina Guimarães Gobbo,Carolina F. Pereira Costa,Carolina F. Pereira Costa,Danilo Grünig Humberto da Silva,Eduardo Alves de Almeida,Rejane M. Góes +6 more
TL;DR: In prostate, melatonin administration normalized GST activity at both ages and mitigated GPx at short-term and CAT at long-term diabetes, demonstrating its effective antioxidant role, even at low dosages.
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Gills as a glutathione-dependent metabolic barrier in Pacific oysters Crassostrea gigas: Absorption, metabolism and excretion of a model electrophile.
Rafael Trevisan,Danielle Ferraz Mello,Gabriel Delapedra,Danilo Grünig Humberto da Silva,Miriam Arl,Naissa Maria Danielli,Marc Metian,Eduardo Alves de Almeida,Alcir Luiz Dafre +8 more
TL;DR: Biokinetic modeling of the MAP supports the fast CDNB uptake and metabolism, and indicated that while gills are a key organ for absorption, initial biotransformation, and likely metabolite excretion, hemolymph is a possible milieu for metabolite transport along different tissues.
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Decreased malondialdehyde levels in fish (Astyanax altiparanae) exposed to diesel: Evidence of metabolism by aldehyde dehydrogenase in the liver and excretion in water
TL;DR: The results suggest that the decreased MDA levels after exposure of lambari to diesel oil pollutant probably reflects an association between enhanced antioxidant protection, MDA metabolism, and MDA excretion in water.