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Dariusz Lange

Researcher at Curie Institute

Publications -  144
Citations -  2463

Dariusz Lange is an academic researcher from Curie Institute. The author has contributed to research in topics: Cancer & Thyroid. The author has an hindex of 24, co-authored 139 publications receiving 2131 citations. Previous affiliations of Dariusz Lange include Shandong University.

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Gene expression profile of papillary thyroid cancer: sources of variability and diagnostic implications.

TL;DR: The results prove that the gene expression signal of PTC is easily detectable even when cancer cells do not prevail over tumor stroma and propose a potent molecular classifier able to discriminate between PTC and nonmalignant thyroid in more than 90% of investigated samples.
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Correction: Corrigendum: Differences in the transcriptome of medullary thyroid cancer regarding the status and type of RET gene mutations

TL;DR: In this Article, an affiliation for Bartosz Wojtas was omitted and the correct affiliations are listed below: Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of On cancerology, Gliwice Branch, Poland.
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Estimation of Risk of Inherited Medullary Thyroid Carcinoma in Apparent Sporadic Patients

TL;DR: The frequency of inherited disease among apparent sporadic medullary thyroid carcinoma patients is close to 10% in the Polish population of MTC patients, and the extended analysis of all known RET proto-oncogene mutation sites is obligatory in patients younger than 45 years at diagnosis, but the need to analyze the impact of rarer mutations in older patients is seen.
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Diagnostic and therapeutic guidelines for gastro-entero-pancreatic neuroendocrine neoplasms (recommended by the Polish Network of Neuroendocrine Tumours).

TL;DR: The proposed recommendations by Polish and foreign experts representing different fields of medicine (endocrinology, gastroenterology, surgery, oncology, nuclear medicine and pathology) will be helpful in the diagnosis and treatment of GEP NENs patients.