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Darryl L. Hadsell

Researcher at Baylor College of Medicine

Publications -  67
Citations -  4695

Darryl L. Hadsell is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Mammary gland & Lactation. The author has an hindex of 32, co-authored 66 publications receiving 4432 citations. Previous affiliations of Darryl L. Hadsell include United States Department of Agriculture & Texas Medical Center.

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The Genome Sequence of Taurine Cattle: A Window to Ruminant Biology and Evolution

Christine G. Elsik, +328 more
- 24 Apr 2009 - 
TL;DR: To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage and provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.
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GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow.

TL;DR: It is concluded that the GLP-2-induced stimulation of blood flow is mediated by vasoactive neurotransmitters that are colocalized with GLp-2R in 2 functionally distinct cell types within the gastrointestinal tract.
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Regulation of milk protein gene expression

TL;DR: Studies using both transgenic mice and transfected mammary epithelial cells have established that composite response elements containing multiple binding sites for several transcription factors mediate the hormonal and developmental regulation of milk protein gene expression.
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Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor

TL;DR: A novel animal model that involves transgenic expression of a fusion receptor that is constitutively activated by homodimerization is described that should provide new opportunities for further understanding how aberrant IGF-IR signaling leads to tumorigenesis and for optimizing novel antagonists of the receptor kinase.
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Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression.

TL;DR: Histological analysis of mammary tissue from mice overexpressing des(1-3)hIGF-I showed incomplete mammary involution, ductile hypertrophy, and loss of secretory lobules associated with increased deposition of collagen, believed to occur through autocrine and paracrine effects of des( 1-3)-hIGf-I on both epithelial and stromal cells.