D
David Baltimore
Researcher at California Institute of Technology
Publications - 882
Citations - 168784
David Baltimore is an academic researcher from California Institute of Technology. The author has contributed to research in topics: RNA & Virus. The author has an hindex of 203, co-authored 876 publications receiving 162955 citations. Previous affiliations of David Baltimore include Thomas Jefferson University & Johns Hopkins University.
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Size of murine RNA tumor virus-specific nuclear RNA molecules.
TL;DR: The size distribution of virus-specific RNA was determined before and after denaturation, and it was found that most of the virus- Specific RNA had a sedimentation coefficient of 35S or lower, but a small fraction of the nuclear virus- specific RNA sedimented more rapidly than 35S RNA even afterDenaturation.
Journal ArticleDOI
Identification of the Vesicular Stomatitis Virus Large Protein as a Unique Viral Protein
TL;DR: Its synthesis relative to the other VSV proteins was studied under conditions of inhibition of initiation of protein synthesis, and its tryptic peptides were compared to those of the other vesicular stomatitis virus proteins.
Protein Sorting: Organelle Biogenesis and Protein Secretion
Harvey F. Lodish,Arnold Berk,S Lawrence Zipursky,Paul Matsudaira,David Baltimore,James Darnell +5 more
Patent
Intracellular method of inhibiting hiv in mammalian cells
TL;DR: In this article, an intracellular method of inhibiting HIV in mammalian cells, in which a recombinant construct is introduced into the cells, is described, which includes the HIV long terminal repeat (LTR) or a portion of the HIV LTR which includes a functional HIV promoter and DNA of non-HIV origin encoding a product which is toxic to HIV-infected cells, when present in such cells alone or in conjunction with a selected substance.
Journal ArticleDOI
In vitro transcription of immunoglobulin genes in a B-cell extract: effects of enhancer and promoter sequences.
Ranjan Sen,David Baltimore +1 more
TL;DR: The development of an in vitro transcription system from cells of the B lymphoid lineage is reported, and it is observed that the addition of polyethylene glycol led to a B-cell extract-specific suppression of transcription from a template that carries an immunoglobulin enhancer.