D
David Baltimore
Researcher at California Institute of Technology
Publications - 882
Citations - 168784
David Baltimore is an academic researcher from California Institute of Technology. The author has contributed to research in topics: RNA & Virus. The author has an hindex of 203, co-authored 876 publications receiving 162955 citations. Previous affiliations of David Baltimore include Thomas Jefferson University & Johns Hopkins University.
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Letter to the editorRetraction: Altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged Mu heavy chain gene
Patent
Antigen specific t cell therapy
Lili Yang,David Baltimore +1 more
TL;DR: In this article, a polynucleotide encoding a T cell receptor with the desired specificity is used to generate T cells of the desired type and specificity in a host, which are then transferred to the host where they develop into mature, functional immune cells.
Journal ArticleDOI
A TLR4 agonist synergizes with dendritic cell-directed lentiviral vectors for inducing antigen-specific immune responses.
Liang Xiao,Jocelyn T. Kim,Matthew L. M. Lim,Bingbing Dai,Lili Yang,Steven G. Reed,David Baltimore,Pin Wang +7 more
TL;DR: This study investigated the adjuvanting capacity of glucopyranosyl lipid A (GLA), a chemically synthesized TLR4 agonist, to boost antigen-specific immunity elicited by DC-directed lentiviral vectors (DC-LV) and found that stimulation by this agonist in vitro can activate DCs in aTLR4-dependent manner.
Journal ArticleDOI
Recombinants within the tyrosine kinase region of v-abl and v-src identify a v-abl segment that confers lymphoid specificity.
TL;DR: It is concluded that the specificity within the kinase domain determines the particular biological behavior of protein-tyrosine kinase oncogenes.