D
David Baltimore
Researcher at California Institute of Technology
Publications - 882
Citations - 168784
David Baltimore is an academic researcher from California Institute of Technology. The author has contributed to research in topics: RNA & Virus. The author has an hindex of 203, co-authored 876 publications receiving 162955 citations. Previous affiliations of David Baltimore include Thomas Jefferson University & Johns Hopkins University.
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Engineering poliovirus as a vaccine vector for the expression of diverse antigens
Raul Andino,Deborah Silvera,Shelley D. Suggett,Philip Achacoso,Philip Achacoso,Christopher J. Miller,David Baltimore,David Baltimore,Mark B. Feinberg +8 more
TL;DR: Poliovirus recombinants were constructed by fusing exogenous peptides and an artificial cleavage site for viral protease 3Cpro to the amino terminus of the viral polyprotein to retain exogenous sequences through successive rounds of replication in culture and in vivo.
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Maturation of Viral Proteins in Cells Infected With Temperature-Sensitive Mutants of Vesicular Stomatitis Virus
TL;DR: Results are consistent with a model of virion formation involving coalescence of soluble nucleocapsid and soluble M protein with G protein already in the plasma membrane, and G protein behaved as in cells infected by mutants in N protein.
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Interaction of HeLa cell proteins with RNA.
David Baltimore,Alice S. Huang +1 more
TL;DR: A number of lines of evidence indicate that binding factor is a heterogeneous collection of soluble proteins which are bound to RNA by ionic forces and are probably not very basic.
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Alternative mRNA splicing in cancer immunotherapy
TL;DR: The promise of analysing mRNA processing events in cancer cells, with an emphasis on mRNA splicing, for the identification of potential new targets for cancer immunotherapy is discussed.
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Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination
TL;DR: The results indicate that the N-terminal one-third of RAG-1, including a zinc-finger-like domain, and an acidic domain of R AG-2 are dispensable for activating V(D)J recombination in a fibroblast, although they contribute quantitatively.