D
David Baltimore
Researcher at California Institute of Technology
Publications - 882
Citations - 168784
David Baltimore is an academic researcher from California Institute of Technology. The author has contributed to research in topics: RNA & Virus. The author has an hindex of 203, co-authored 876 publications receiving 162955 citations. Previous affiliations of David Baltimore include Thomas Jefferson University & Johns Hopkins University.
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Poliovirus replicase stimulation by terminal uridylyl transferase.
TL;DR: A model for minus strand synthesis by poliovirus replicase is presented, based on the hypothesis that a terminal uridylyl transferase can participate in initiation, and preliminary evidence that it may be responsible for host factor-like activity is provided.
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HIV-1 Gag-specific immunity induced by a lentivector-based vaccine directed to dendritic cells.
TL;DR: Results demonstrate that this dendritic cell (DC)-directed LV immunization is a potent modality for eliciting anti-HIV immune responses.
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Nuclear factor NF-kappa B can interact functionally with its cognate binding site to provide lymphoid-specific promoter function.
Thomas Wirth,David Baltimore +1 more
TL;DR: The same nuclear factor can act as a positive activator of both enhancer and promoter function, suggesting that the two functions involve similar events in the transcription process.
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Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood.
Songming Peng,Jesse M. Zaretsky,Alphonsus H. C. Ng,Alphonsus H. C. Ng,William Chour,William Chour,Michael T. Bethune,Jongchan Choi,Alice Hsu,Elizabeth Holman,Xiaozhe Ding,Katherine Guo,Jungwoo Kim,Alexander M. Xu,Alexander M. Xu,John E. Heath,Won Jun Noh,Jing Zhou,Yapeng Su,Yapeng Su,Yue Lu,Yue Lu,Jami McLaughlin,Donghui Cheng,Owen N. Witte,David Baltimore,Antoni Ribas,James R. Heath,James R. Heath +28 more
TL;DR: A sensitive method for the enumeration and isolation of neoantigen-specific CD8+ T cells from small samples of patient tumor or blood that exhibits superior recovery of antigen-specific T cell populations relative to literature approaches is described.
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Inhibition of transcription factor activity by poliovirus
TL;DR: Results indicate that at least one factor required for specific transcription by polymerase II is deficient in extracts from poliovirus-infected cells.