D
David H. O’Connor
Researcher at University of Wisconsin-Madison
Publications - 376
Citations - 17589
David H. O’Connor is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Simian immunodeficiency virus & Virus. The author has an hindex of 60, co-authored 349 publications receiving 14915 citations. Previous affiliations of David H. O’Connor include University of Southampton & Harvard University.
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Journal ArticleDOI
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
Florencia Pereyra,Xiaoming Jia,Paul J. McLaren,Amalio Telenti,de Bakker Pi,Bruce D. Walker,Stephan Ripke,Chanson J. Brumme,Sara L. Pulit,Mary Carrington,Carl M. Kadie,Jonathan M. Carlson,David E. Heckerman,Graham Rr,Robert M. Plenge,Steven G. Deeks,Gianniny L,Gabriel Crawford,Jean C. Sullivan,Elena Gonzalez,Davies L,Amy L. Camargo,Jamie Moore,Beattie N,Soumi Gupta,Crenshaw A,N P Burtt,Candace Guiducci,Namrata Gupta,Gao X,Qi Y,Yuko Yuki,Alicja Piechocka-Trocha,Emily Cutrell,Rachel Rosenberg,Kristin Moss,Lemay P,Jacqueline G. O'Leary,Schaefer T,Verma P,I Tóth,Brian L. Block,Brett Baker,Alissa C. Rothchild,Lian J,Jacqueline Proudfoot,Donna Marie Alvino,Seanna Vine,Marylyn M. Addo,Todd M. Allen,Marcus Altfeld,Matthew R. Henn,Le Gall S,Hendrik Streeck,David W. Haas,Daniel R. Kuritzkes,Gregory K. Robbins,Robert W. Shafer,Roy M. Gulick,Cecilia M. Shikuma,Richard Haubrich,Sharon A. Riddler,Paul E. Sax,Eric S. Daar,Heather J. Ribaudo,Brian K. Agan,Agarwal S,Ryan Ahern,Allen Bl,Altidor S,Altschuler El,Ambardar S,Kathryn Anastos,Brenna L. Anderson,Anderson,Andrady U,Antoniskis D,David R. Bangsberg,Barbaro D,Barrie W,Bartczak J,Barton S,Basden P,Nesli Basgoz,Suzane Bazner,Nicholas Bellos,Benson Am,Judith Berger,Bernard Nf,Bernard Am,Christopher E. Birch,Bodner Sj,Robert K. Bolan,Boudreaux Et,Meg Bradley,Braun Jf,Brndjar Je,Stephen J. Brown,Brown K,Sheldon T. Brown,Burack J,Bush Lm,Cafaro,Campbell O,Justin Campbell,Carlson Rh,Carmichael Jk,Casey Kk,Cavacuiti C,Celestin G,Stephen T. Chambers,Chez N,Lisa M. Chirch,Cimoch Pj,Daniel E. Cohen,Cohn Le,Brian Conway,David A. Cooper,Cornelson B,Cox Dt,Cristofano Mv,Cuchural G,Julie Czartoski,Dahman Jm,Jennifer S. Daly,Benjamin T. Davis,Kenneth L. Davis,Davod Sm,Edwin DeJesus,Craig A. Dietz,Dunham E,Dunn Me,Todd B. Ellerin,J. J. Eron,John Fangman,Farel Ce,Ferlazzo H,Sarah Fidler,Fleenor-Ford A,Frankel R,Kenneth A. Freedberg,French Nk,Jonathan D. Fuchs,Jon Fuller,Gaberman J,Joel E. Gallant,Rajesh T. Gandhi,Garcia E,Garmon D,J. Gathe,Gaultier Cr,Gebre W,Gilman Fd,Gilson I,Paul A. Goepfert,M. S. Gottlieb,Claudia Goulston,Groger Rk,Gurley Td,Haber S,Hardwicke R,W D Hardy,P. R. Harrigan,Trevor Hawkins,Sonya L. Heath,Frederick Hecht,Henry Wk,Hladek M,Hoffman Rp,James Horton,Hsu Rk,Gregory D Huhn,Peter W. Hunt,Hupert Mj,Illeman Ml,Hans Jaeger,Robert M. Jellinger,Mina John,Jennifer Johnson,Kristin Johnson,Johnson H,Kevin M. Johnson,Joly J,Wilbert C. Jordan,Carol A. Kauffman,Khanlou H,Killian Rk,Arthur Y. Kim,Kim Dd,Kinder Ca,Kirchner Jt,Laura Kogelman,Erna M. Kojic,Korthuis Pt,Kurisu W,Douglas S. Kwon,Melissa Lamar,Harry Lampiris,Lanzafame M,Michael M. Lederman,Lee Dm,Lee Jm,Lee Mj,Lee Et,Lemoine J,Jay A. Levy,Josep M. Llibre,Liguori Ma,Susan J. Little,Anne Y. Liu,Lopez Aj,Mona R. Loutfy,Loy D,Mohammed Dy,Man A,Michael K. Mansour,Vincent C. Marconi,Martin Markowitz,R. Marques,Jeffrey N. Martin,Hal Martin,Kenneth H. Mayer,MJ McElrath,McGhee Ta,Barbara H. McGovern,Katherine McGowan,McIntyre D,Mcleod Gx,Menezes P,Mesa G,Craig E. Metroka,Dirk Meyer-Olson,Miller Ao,Montgomery K,Karam Mounzer,Ellen H. Nagami,Nagin I,Nahass Rg,Nelson Mo,Nielsen C,Norene Dl,David H. O’Connor,Bisola O. Ojikutu,Jason F. Okulicz,Oladehin Oo,Oldfield Ec rd,Susan Olender,Mario A. Ostrowski,William F. Owen,Pae E,Parsonnet J,Pavlatos Am,Perlmutter Am,Pierce Mn,Pincus Jm,Pisani L,Price Lj,Laurie A. Proia,Prokesch Rc,Pujet Hc,Moti Ramgopal,Almas Rathod,Rausch M,Ravishankar J,Frank S. Rhame,Richards Cs,Douglas D. Richman,Rodes B,Rodriguez M,Rose Rc rd,Eric S. Rosenberg,Daniel I. Rosenthal,Ross Pe,Diana Rubin,Rumbaugh E,Saenz L,Michelle R Salvaggio,Sanchez Wc,Sanjana Vm,Steven Santiago,Schmidt W,Hanneke Schuitemaker,Sestak Pm,P. Shalit,Shay W,Shirvani Vn,Silebi Vi,Sizemore Jm,Paul R. Skolnik,Marcia Sokol-Anderson,James M. Sosman,Stabile P,Jack T. Stapleton,Starrett S,Stein F,Hans-Jürgen Stellbrink,Sterman Fl,Valerie E. Stone,David Stone,Giuseppe Tambussi,Randy Taplitz,Ellen Tedaldi,Theisen W,Ramon A. Torres,Tosiello L,Cécile Tremblay,Tribble Ma,Trinh Pd,Tsao A,Ueda P,Vaccaro A,Valadas E,Vanig Tj,Vecino I,Vega Vm,Veikley W,Wade Bh,Walworth C,Wanidworanun C,Doug Ward,Warner Da,Rainer Weber,Daniel P. Webster,Weis S,David Wheeler,D. White,Edmund Wilkins,Alan Winston,Wlodaver Cg,van't Wout A,Wright Dp,Otto O. Yang,Yurdin Dl,Zabukovic Bw,Kimon C. Zachary,Zeeman B,Zhao M +336 more
TL;DR: Differences in binding to viral peptide antigens by HLA may be the major factors underlying genetic differences between HIV controllers and progressors, and genome-wide association results implicate the nature of the HLA–viral peptide interaction as the major factor modulating durable control of HIV infection.
Journal ArticleDOI
Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components
Keith Pardee,Alexander A. Green,Melissa K. Takahashi,Dana Braff,Dana Braff,Dana Braff,Guillaume Lambert,Guillaume Lambert,Jeong Wook Lee,Tom Ferrante,Duo Ma,Nina M. Donghia,Melina Fan,Nichole M. Daringer,Irene Bosch,Dawn M. Dudley,David H. O’Connor,Lee Gehrke,Lee Gehrke,James J. Collins +19 more
TL;DR: A pipeline for the rapid design, assembly, and validation of cell-free, paper-based sensors for the detection of the Zika virus RNA genome is reported, which detect clinically relevant concentrations of Zika virus sequences and demonstrate specificity against closely related Dengue virus sequences.
Journal ArticleDOI
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.
Todd M. Allen,David H. O’Connor,Peicheng Jing,John L. Dzuris,Bianca R. Mothé,Thorsten U. Vogel,Ed Dunphy,Max E. Liebl,Carol Emerson,Nancy A. Wilson,Kevin J. Kunstman,Xiaochi Wang,David B. Allison,Austin L. Hughes,Ronald C. Desrosiers,John D. Altman,Steven M. Wolinsky,Alessandro Sette,David I. Watkins +18 more
TL;DR: It is shown that Tat-specific CD8-positive T-lymphocyte responses select for new viral escape variants during the acute phase of infection, and suggests that responses against viral proteins that are expressed early during the viral life cycle might be attractive targets for HIV vaccine development.
Journal ArticleDOI
Enhancing studies of the connectome in autism using the autism brain imaging data exchange II
Adriana Di Martino,David H. O’Connor,David H. O’Connor,Bosi Chen,Kaat Alaerts,Jeffrey S. Anderson,Michal Assaf,Michal Assaf,Joshua H. Balsters,Leslie C. Baxter,Anita Beggiato,Sylvie Bernaerts,Laura M. E. Blanken,Susan Y. Bookheimer,B. Blair Braden,B. Blair Braden,Lisa Byrge,F. Xavier Castellanos,F. Xavier Castellanos,Mirella Dapretto,Richard Delorme,Damien A. Fair,Inna Fishman,Jacqueline Fitzgerald,Louise Gallagher,R. Joanne Jao Keehn,Daniel P. Kennedy,Janet E. Lainhart,Janet E. Lainhart,Beatriz Luna,Stewart H. Mostofsky,Ralph-Axel Müller,Ralph-Axel Müller,Mary Beth Nebel,Joel T. Nigg,Joel T. Nigg,Kirsten O'Hearn,Marjorie Solomon,Roberto Toro,Chandan J. Vaidya,Nicole Wenderoth,Nicole Wenderoth,Tonya White,R. Cameron Craddock,Catherine Lord,Bennett L. Leventhal,Michael P. Milham,Michael P. Milham +47 more
TL;DR: This new multisite open-data resource is an aggregate of resting state functional magnetic resonance imaging (MRI) and corresponding structural MRI and phenotypic datasets and includes a range of psychiatric variables to inform the understanding of the neural correlates of co-occurring psychopathology.
Journal ArticleDOI
Reversion of CTL escape-variant immunodeficiency viruses in vivo.
Thomas C. Friedrich,Elizabeth J. Dodds,Levi Yant,Lara Vojnov,Richard Rudersdorf,Candice Cullen,David T. Evans,Ronald C. Desrosiers,Bianca R. Mothé,John Sidney,Alessandro Sette,Kevin J. Kunstman,Steven M. Wolinsky,Michael Piatak,Jeffrey D. Lifson,Austin L. Hughes,Nancy A. Wilson,David H. O’Connor,David I. Watkins +18 more
TL;DR: It is concluded that escape from CTL responses may exact a cost to viral fitness, and in the absence of selective pressure upon transmission to new hosts, these original escape mutations can be lost.