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David Hahn

Researcher at Cincinnati Children's Hospital Medical Center

Publications -  14
Citations -  5510

David Hahn is an academic researcher from Cincinnati Children's Hospital Medical Center. The author has contributed to research in topics: Physiologically based pharmacokinetic modelling & Autophagy. The author has an hindex of 9, co-authored 14 publications receiving 5005 citations. Previous affiliations of David Hahn include Boston Children's Hospital.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 - 
Journal ArticleDOI

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Daniel J. Klionsky, +2522 more
- 01 Jan 2016 - 
TL;DR: Author(s): Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; A Frozena, AA; Adachi, H, Adeli, K, Adhihetty, PJ; Adler, SG; Agam, G; Agarwal, R; Aghi, MK; Agnello, M; Agostinis, P; Aguilar, PV; Aguirre-Ghis
Journal ArticleDOI

Influence of OCT1 Ontogeny and Genetic Variation on Morphine Disposition in Critically Ill Neonates: Lessons From PBPK Modeling and Clinical Study.

David Hahn, +10 more
- 01 Mar 2019 - 
TL;DR: A physiologically based pharmacokinetic model for morphine that accounted for OCT1 ontogeny and PG effect in post‐term neonates adequately described the clinically observed variability in morphine PKs.
Journal ArticleDOI

A Theoretical Physiologically-Based Pharmacokinetic Approach to Ascertain Covariates Explaining the Large Interpatient Variability in Tacrolimus Disposition.

Chie Emoto, +9 more
TL;DR: The utility of PBPK modeling as a tool for mechanistic and quantitative assessment of the impact of patient physiological differences on observed large PK variability is demonstrated.