D
David I. McLean
Researcher at University of British Columbia
Publications - 115
Citations - 8023
David I. McLean is an academic researcher from University of British Columbia. The author has contributed to research in topics: Raman spectroscopy & Skin cancer. The author has an hindex of 39, co-authored 114 publications receiving 7463 citations. Previous affiliations of David I. McLean include Vancouver Coastal Health & BC Cancer Agency.
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Near-infrared Raman spectroscopy for optical diagnosis of lung cancer
TL;DR: NIR Raman spectroscopy provides significant potential for the noninvasive diagnosis of lung cancers in vivo based on the optic evaluation of biomolecules, according to the results of this exploratory study.
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Automated Autofluorescence Background Subtraction Algorithm for Biomedical Raman Spectroscopy
TL;DR: An improved automated algorithm for fluorescence removal has been developed based on modified multi-polynomial fitting, but with the addition of a peak-removal procedure during the first iteration, and a statistical method to account for signal noise effects.
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Sunlight Exposure, Pigmentary Factors, and Risk of Nonmelanocytic Skin Cancer: I. Basal Cell Carcinoma
Richard P. Gallagher,Gerry B. Hill,Chris Bajdik,Shirley Fincham,Andrew J. Coldman,David I. McLean,William J. Threlfall +6 more
TL;DR: The lack of association between cumulative sun exposure and BCC contradicts conventional wisdom about the cause of this tumor, and the increased risk with sun exposure at age 0 to 19 years suggests that childhood and adolescence may be critical periods for establishing adult risk for BCC.
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Dullrazor® : A software approach to hair removal from images
Tim K. Lee,Vincent To Yee Ng,Richard P. Gallagher,Richard P. Gallagher,Andrew J. Coldman,David I. McLean,David I. McLean +6 more
TL;DR: This paper presents a method to remove hairs from an image using a pre-processing program, called DullRazor, that enables the segmentation program to achieve satisfactory results.
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Real-time Raman Spectroscopy for In Vivo Skin Cancer Diagnosis
TL;DR: It is established that real-time Raman spectroscopy can be used to distinguish malignant from benign skin lesions with good diagnostic accuracy comparable with clinical examination and other optical-based methods.