D
David J. Craik
Researcher at University of Queensland
Publications - 866
Citations - 43046
David J. Craik is an academic researcher from University of Queensland. The author has contributed to research in topics: Cyclotides & Cyclotide. The author has an hindex of 100, co-authored 866 publications receiving 38492 citations. Previous affiliations of David J. Craik include University of Washington & University of California, Los Angeles.
Papers
More filters
Journal ArticleDOI
Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature
Paul G. Arnison,Mervyn J. Bibb,Gabriele Bierbaum,Albert A. Bowers,Tim S. Bugni,Grzegorz Bulaj,Julio A. Camarero,Dominic J. Campopiano,Gregory L. Challis,Jon Clardy,Paul D. Cotter,David J. Craik,Michael J. Dawson,Elke Dittmann,Stefano Donadio,Pieter C. Dorrestein,K. D. Entian,Michael A. Fischbach,John S. Garavelli,Ulf Göransson,Christian W. Gruber,Daniel H. Haft,Thomas Hemscheidt,Christian Hertweck,Colin Hill,Alexander R. Horswill,Marcel Jaspars,Wendy L. Kelly,Judith P. Klinman,Oscar P. Kuipers,A. James Link,Wen Liu,Mohamed A. Marahiel,Douglas A. Mitchell,Gert N. Moll,Bradley S. Moore,Rolf Müller,Satish K. Nair,Ingolf F. Nes,Gillian E. Norris,Baldomero M. Olivera,Hiroyasu Onaka,Mark L. Patchett,Joern Piel,Joern Piel,Martin J. T. Reaney,Sylvie Rebuffat,R. Paul Ross,Hans-Georg Sahl,Eric W. Schmidt,Michael E. Selsted,Konstantin Severinov,Ben Shen,Kaarina Sivonen,Leif Smith,Torsten Stein,Roderich D. Süssmuth,John R. Tagg,Gong-Li Tang,Andrew W. Truman,John C. Vederas,Christopher T. Walsh,Jonathan D. Walton,Silke C. Wenzel,Joanne M. Willey,Wilfred A. van der Donk +65 more
TL;DR: This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products.
Journal ArticleDOI
The Future of Peptide‐based Drugs
TL;DR: The suite of currently used drugs can be divided into two categories - traditional'small molecule' drugs with typical molecular weights of 5000 Da that are not orally bioavailable and need to be delivered via injection as mentioned in this paper.
Journal ArticleDOI
Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif
TL;DR: The structural features of the two apparent subfamilies of the CCK peptides which may be significant for the likely defense related role of these peptides within plants are defined.
Journal ArticleDOI
A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides.
TL;DR: This structural motif appears to be one of the smallest stable globular domains found in proteins and is commonly used in toxins and inhibitors that act by blocking the function of larger protein receptors such as ion channels or proteases.
Journal ArticleDOI
Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?
TL;DR: The structural biology described herein for Abeta(1-40) suggests that the C-terminal two-thirds of the peptide is an alpha-helix in membrane-like environments, deprotonation of two acidic amino acids in the helix promotes a helix-coil conformational transition that precedes aggregation.