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David Jukam
Researcher at Stanford University
Publications - 20
Citations - 1274
David Jukam is an academic researcher from Stanford University. The author has contributed to research in topics: Chromatin & RNA. The author has an hindex of 11, co-authored 19 publications receiving 1000 citations. Previous affiliations of David Jukam include New York University & Rockefeller University.
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Journal ArticleDOI
Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes
Karina Del Punta,Trese Leinders-Zufall,Ivan Rodriguez,Ivan Rodriguez,David Jukam,Charles J. Wysocki,Sonoko Ogawa,Frank Zufall,Peter Mombaerts +8 more
TL;DR: The behavioural impairment and chemosensory deficit support a role of V1r receptors as pheromone receptors, and the deletion of a ∼600-kilobase genomic region that contains a cluster of 16 intact V1R genes is deleted.
Journal ArticleDOI
Zygotic Genome Activation in Vertebrates.
TL;DR: Progress in understanding vertebrate ZGA dynamics in frogs, fish, mice, and humans is reviewed to explore differences and emphasize common features.
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Histone titration against the genome sets the DNA-to-cytoplasm threshold for the Xenopus midblastula transition
TL;DR: The observations support a model for MBT regulation by DNA-based titration and suggest that depletion of free histones regulates the MBT and shows how a constant concentration DNA binding molecule can effectively measure the amount of cytoplasm per genome to coordinate division, growth, and development.
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Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts.
Jason C. Bell,David Jukam,Nicole A. Teran,Viviana I. Risca,Owen K. Smith,Whitney L Johnson,Jan M. Skotheim,William J. Greenleaf,Aaron F. Straight +8 more
TL;DR: It is shown that ChAR-seq provides unbiased, de novo identification of targets of chromatin-bound RNAs including nascent transcripts, chromosome-specific dosage compensation ncRNAs, and genome-wide trans-associated RNAs involved in co-transcriptional RNA processing.
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Opposite feedbacks in the Hippo pathway for growth control and neural fate
David Jukam,Baotong Xie,Jens Rister,David Terrell,Mark Charlton-Perkins,Daniela Pistillo,Brian Gebelein,Claude Desplan,Tiffany Cook +8 more
TL;DR: The transcriptional output of the Hippo pathway in photoreceptor differentiation, as in cell proliferation, is mediated through the factors Yki and Scalloped, and illustrates how molecular signaling pathways can adopt context-specific regulation.