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David K. Ann

Researcher at City of Hope National Medical Center

Publications -  150
Citations -  17623

David K. Ann is an academic researcher from City of Hope National Medical Center. The author has contributed to research in topics: Autophagy & Cancer. The author has an hindex of 47, co-authored 137 publications receiving 14255 citations. Previous affiliations of David K. Ann include National Institutes of Health & University of Southern California.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance.

Tianyi Wang, +16 more
- 09 Jan 2018 - 
TL;DR: It is demonstrated that JAK/STAT3 regulates lipid metabolism, which promotes breast CSCs (BCSCs) and cancer chemoresistance, and human breast-cancer-derived data suggest that the STAT3-CPT1B-FAO pathway promotes cancer cell stemness and Chemoresistance.
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Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation

Min Pan, +19 more
- 12 Sep 2016 - 
TL;DR: It is shown that the core region of solid tumours displayed glutamine deficiency compared with other amino acids, which led to dramatic histone hypermethylation due to decreased α-ketoglutarate levels, a key cofactor for the Jumonji-domain-containing histone demethylases.