D
David Light
Researcher at Life Technologies
Publications - 17
Citations - 2557
David Light is an academic researcher from Life Technologies. The author has contributed to research in topics: Nucleic acid & Particle. The author has an hindex of 5, co-authored 17 publications receiving 2397 citations.
Papers
More filters
Journal ArticleDOI
An integrated semiconductor device enabling non-optical genome sequencing
Jonathan M. Rothberg,Wolfgang Hinz,Todd Rearick,Jonathan Schultz,William J. Mileski,Melville Davey,John H. Leamon,Kim L. Johnson,Mark James Milgrew,Matthew D. Edwards,Jeremy Hoon,Jan Fredrik Simons,David Marran,Jason W. Myers,John F. Davidson,Annika Branting,John Nobile,Bernard P. Puc,David Light,Travis A. Clark,Martin Huber,Jeffrey T. Branciforte,Isaac B. Stoner,Simon Cawley,Michael R. Lyons,Yutao Fu,Nils Homer,Marina Sedova,Xin Miao,Brian Reed,Jeffrey Sabina,Erika Feierstein,Michelle Schorn,Mohammad Alanjary,Eileen T. Dimalanta,Devin Dressman,Rachel Kasinskas,Tanya Sokolsky,Jacqueline A. Fidanza,Eugeni Namsaraev,Kevin McKernan,Alan Williams,G. Thomas Roth,James Bustillo +43 more
TL;DR: A DNA sequencing technology in which scalable, low-cost semiconductor manufacturing techniques are used to make an integrated circuit able to directly perform non-optical DNA sequencing of genomes, showing its robustness and scalability by producing ion chips with up to 10 times as many sensors and sequencing a human genome.
Patent
Scaffolded Nucleic Acid Polymer Particles and Methods of Making and Using
TL;DR: In this article, the authors provide particle compositions having applications in nucleic acid analysis, which allow polynucleotides to be attached throughout their volumes for higher loading capacities than those achievable solely with surface attachment.
Patent
Polymer particles, nucleic acid polymer particles and methods of making and using the same
David Light,Barnett B. Rosenblum +1 more
TL;DR: In this paper, the authors have discussed methods of making polymer particles, including the steps of: making an aqueous gel reaction mixture, forming an emulsion having dispersed micelles of the reaction mixture in a continuous phase, and adding an initiator oil comprising at least one polymerization initiator to the continuous phase.
Patent
Methods of Making Libraries of Nucleic Acids Using Porous Particles
TL;DR: In this article, the authors provide particle compositions having applications in nucleic acid analysis, which allow polynucleotides to be attached throughout their volumes for higher loading capacities than those achievable solely with surface attachment.
Patent
Immobilized buffer particles and uses thereof
TL;DR: In this article, the disclosure relates to novel particle compositions and methods of making said compositions having applications in nucleic acid analysis, as well as apparatuses and systems for the same.