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David M. Berson
Researcher at Brown University
Publications - 108
Citations - 15905
David M. Berson is an academic researcher from Brown University. The author has contributed to research in topics: Intrinsically photosensitive retinal ganglion cells & Melanopsin. The author has an hindex of 43, co-authored 105 publications receiving 14271 citations. Previous affiliations of David M. Berson include Massachusetts Institute of Technology.
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Journal ArticleDOI
Phototransduction by retinal ganglion cells that set the circadian clock.
TL;DR: It is shown that retinal ganglion cells innervating the SCN are intrinsically photosensitive, and depolarized in response to light even when all synaptic input from rods and cones was blocked.
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Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity
TL;DR: It is shown that melanopsin is present in cell bodies, dendrites, and proximal axonal segments of a subset of rat RGCs, most likely the visual pigment of phototransducing R GCs that set the circadian clock and initiate other non–image-forming visual functions.
Journal ArticleDOI
Measuring and using light in the melanopsin age
Robert J. Lucas,Stuart N. Peirson,David M. Berson,Timothy M. Brown,Howard M. Cooper,Charles A. Czeisler,Mariana G. Figueiro,Paul D. Gamlin,Steven W. Lockley,John O’Hagan,Luke L. A. Price,Ignacio Provencio,Debra J. Skene,George C. Brainard +13 more
TL;DR: A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers.
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Central projections of melanopsin-expressing retinal ganglion cells in the mouse
Samer Hattar,Monica Kumar,Alexander Park,Patrick Tong,Jonathan Tung,King Wai Yau,David M. Berson +6 more
TL;DR: Staining patterns after monocular enucleation revealed that the projections of these cells are overwhelmingly crossed except for the projection to the SCN, which is bilaterally symmetrical, and that other ganglion cells do contribute at least some retinal input to these targets.
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Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
TL;DR: In the mammalian retina, a small subset of retinal ganglion cells (RGCs) are intrinsically photosensitive, expressing the opsin-like protein melanopsin, and project to brain nuclei involved in non-image-forming visual functions such as pupillary light reflex and circadian photoentrainment as discussed by the authors.