D
David O. Williams
Researcher at Brigham and Women's Hospital
Publications - 268
Citations - 33368
David O. Williams is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & Percutaneous coronary intervention. The author has an hindex of 74, co-authored 268 publications receiving 31920 citations. Previous affiliations of David O. Williams include Brown University & Mayo Clinic.
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Journal ArticleDOI
Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery.
Jeffrey W. Moses,Martin B. Leon,Jeffrey J. Popma,Peter J. Fitzgerald,David R. Holmes,Charles O'Shaughnessy,Ronald P. Caputo,Dean J. Kereiakes,David O. Williams,Paul S. Teirstein,Judith Jaeger,Richard E. Kuntz +11 more
TL;DR: In this randomized clinical trial involving patients with complex coronary lesions, the use of a sirolimus-eluting stent had a consistent treatment effect, reducing the rates of restenosis and associated clinical events in all subgroups analyzed.
Journal ArticleDOI
Universal definition of myocardial infarction.
Kristian Thygesen,Joseph S. Alpert,Harvey D. White,Allan S. Jaffe,Fred S. Apple,Marcello Galvani,Hugo A. Katus,L. Kristin Newby,Jan Ravkilde,Bernard R. Chaitman,Peter Clemmensen,Mikael Dellborg,Hanoch Hod,Pekka Porela,Richard Underwood,Jeroen J. Bax,George A. Beller,Robert O. Bonow,Ernst E. van der Wall,Jean-Pierre Bassand,William Wijns,T. Bruce Ferguson,Philippe Gabriel Steg,Barry F. Uretsky,David O. Williams,Paul W. Armstrong,Elliott M. Antman,Keith A.A. Fox,Christian W. Hamm,E. Magnus Ohman,Maarten L. Simoons,Philip A. Poole-Wilson,Enrique P. Gurfinkel,José-Luis López-Sendón,Prem Pais,Shanti Mendis,Jun-Ren Zhu,Lars Wallentin,Francisco Fernández-Avilés,Kim Fox,Alexander Parkhomenko,Silvia G. Priori,Michal Tendera,Liisa-Maria Voipio-Pulkki,Alec Vahanian,A. John Camm,Raffaele De Caterina,Veronica Dean,Kenneth Dickstein,Gerasimos Filippatos,Christian Funck-Brentano,Irene Hellemans,Steen Dalby Kristensen,Keith McGregor,Udo Sechtem,Sigmund Silber,Petr Widimsky,José Luis Zamorano,João Morais,Sorin J. Brener,Robert A. Harrington,David A. Morrow,Michael J. Lim,Marco A. Martinez-Rios,Steve Steinhubl,Glen N. Levine,W. Brian Gibler,David C. Goff,Marco Tubaro,Darek Dudek,Nawwar Al-Attar +70 more
TL;DR: Information on myocardial infarction attack rates can provide useful data regarding the burden of coronary artery disease within and across populations, especially if standardized data are collected in a manner that demonstrates the distinction between incident and recurrent events.
Journal ArticleDOI
2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Frederick G. Kushner,Mary M. Hand,Sidney C. Smith,Spencer B. King,Jeffrey L. Anderson,Elliott M. Antman,Steven R. Bailey,Eric R. Bates,James C. Blankenship,Donald E. Casey,Lee A. Green,Judith S. Hochman,Alice K. Jacobs,Harlan M. Krumholz,Douglass A. Morrison,Joseph P. Ornato,David L. Pearle,Eric D. Peterson,Michael A. Sloan,Patrick L. Whitlow,David O. Williams +20 more
TL;DR: A primary challenge in the development of clinical practice guidelines is keeping pace with the stream of new data on which recommendations are based as discussed by the authors, and the American College of Cardiology Foundation/American Heart Association (ACCF/AHA) is to respond promptly to new evidence.
Journal ArticleDOI
A Clinical Trial Comparing Three Antithrombotic-Drug Regimens after Coronary-Artery Stenting
Martin B. Leon,Donald S. Baim,Jeffrey J. Popma,Paul C. Gordon,Donald E. Cutlip,Kalon K.L. Ho,Alex Giambartolomei,Daniel J. Diver,David Lasorda,David O. Williams,Stuart J. Pocock,Richard E. Kuntz +11 more
TL;DR: This study compared the efficacy and safety of three antithrombotic-drug regimens — aspirin alone, aspirin and warfarin, and aspirin and ticlopidine — after coronary stenting to prevent stent thrombosis.
Journal ArticleDOI
Initial invasive or conservative strategy for stable coronary disease.
David J. Maron,Judith S. Hochman,Harmony R. Reynolds,Sripal Bangalore,Sean M. O'Brien,William E. Boden,Bernard R. Chaitman,Roxy Senior,Roxy Senior,Jose Lopez-Sendon,Karen P. Alexander,Renato D. Lopes,Leslee J. Shaw,Jeffrey S. Berger,Jonathan D. Newman,Mandeep S. Sidhu,Shaun G. Goodman,Witold Rużyłło,Gilbert Gosselin,Aldo P. Maggioni,Harvey D. White,Balram Bhargava,James K. Min,G.B. John Mancini,Daniel S. Berman,Michael H. Picard,Raymond Y. Kwong,Ziad A. Ali,Ziad A. Ali,Daniel B. Mark,John A. Spertus,Mangalath Narayanan Krishnan,Ahmed Elghamaz,Nagaraja Moorthy,Whady Hueb,Marcin Demkow,Kreton Mavromatis,Kreton Mavromatis,Olga L. Bockeria,Jesús Peteiro,Todd D. Miller,Hanna Szwed,Rolf Doerr,Matyas Keltai,Joseph B. Selvanayagam,P. Gabriel Steg,Claes Held,Claes Held,Shun Kohsaka,Stavroula Mavromichalis,Ruth Kirby,Neal Jeffries,Frank E. Harrell,Frank W. Rockhold,Samuel Broderick,T. Bruce Ferguson,David O. Williams,Robert A. Harrington,Gregg W. Stone,Yves Rosenberg +59 more
TL;DR: Evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years is not found.