D
David Phillips
Researcher at University of Oxford
Publications - 80
Citations - 6191
David Phillips is an academic researcher from University of Oxford. The author has contributed to research in topics: Lysozyme & German. The author has an hindex of 31, co-authored 78 publications receiving 6106 citations.
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Journal ArticleDOI
Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5 angstrom resolution using amino acid sequence data.
D. W. Banner,A. C. Bloomer,Gregory A. Petsko,David Phillips,C. I. Pogson,Ian A. Wilson,P. H. Corran,Anna J. Furth,J. D. Milman,R. E. Offord,J. D. Priddle,S. G. Waley +11 more
TL;DR: Each subunit of triose phosphate isomerase is composed of alternate segments of polypeptide chain in the α- and β-conformations that are arranged to form an inner cylinder of parallel-pleated sheet and a largely helical outer shell.
Journal ArticleDOI
Crystallographic Studies of the Activity of Hen Egg-White Lysozyme
TL;DR: The chemical evidence for the enzymic activity of lysozyme will be discussed in detail by other speakers at this meeting, but in order to describe the crystallographic studies of the interactions between the enzyme and its substrates it is necessary to summarize briefly what was known about them at the beginning of the work.
Journal ArticleDOI
A possible three-dimensional structure of bovine alpha-lactalbumin based on that of hen's egg-white lysozyme.
TL;DR: The biochemical evidence shows that the role of α-lactalbumin in the synthesis of lactose is a complex one requiring direct interaction with the A protein.
Journal ArticleDOI
Crystallographic studies of the dynamic properties of lysozyme
Peter J. Artymiuk,Colin C.F. Blake,D.E.P. Grace,S. J. Oatley,David Phillips,Michael J.E. Sternberg +5 more
TL;DR: It is concluded that protein mobility may play a significant part in biological activity and that X-ray crystallography can contribute to its analysis.